loading...| Preferred Name |
Exenatide |
|
| Synonyms |
ITCA 650 |
|
| Definitions |
A synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the GILA MONSTER lizard (Heloderma suspectum). Exenatide increases CYCLIC AMP levels in pancreatic acinar cells and acts as a GLUCAGON-LIKE PEPTIDE-1 RECEPTOR (GLP-1) agonist and incretin mimetic, enhancing insulin secretion in response to increased glucose levels; it also suppresses inappropriate glucagon secretion and slows gastric emptying. It is used as an anti-diabetic and anti-obesity agent. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000077270 |
|
| altLabel |
ITCA 650 AC 2993 LAR Peptide, Ex4 Exendin 4 Ex4 Peptide AC 2993 Byetta Exendin-4 Bydureon |
|
| AQL |
AA AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR |
|
| cui |
C3714131 C1174290 C3257792 C1636686 C0167117 C1174289 |
|
| DC |
1 |
|
| definition |
A synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the GILA MONSTER lizard (Heloderma suspectum). Exenatide increases CYCLIC AMP levels in pancreatic acinar cells and acts as a GLUCAGON-LIKE PEPTIDE-1 RECEPTOR (GLP-1) agonist and incretin mimetic, enhancing insulin secretion in response to increased glucose levels; it also suppresses inappropriate glucagon secretion and slows gastric emptying. It is used as an anti-diabetic and anti-obesity agent. |
|
| DX |
20190101 |
|
| HN |
2019 (1992) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
9P1872D4OL 0 |
|
| isa |
http://purl.bioontology.org/ontology/MESH/D019440 |
|
| LT |
TRD |
|
| Machine permutation |
2019; EXENATIDE was indexed under PEPTIDES and VENOMS 1992-2018 |
|
| MDA |
20180709 |
|
| MMR |
20230601 |
|
| MN |
D12.644.187 D20.888.300 D23.946.833.300 |
|
| notation |
D000077270 |
|
| PA |
D000097789 D019440 D054795 |
|
| prefLabel |
Exenatide |
|
| RR |
141732-76-5 (Exenatide) |
|
| TERMUI |
T000938584 T533298 T000938586 T000938583 T683761 T533299 T000938585 T000938588 T852658 |
|
| TH |
US FDA SRS (2018) NLM (2012) USAN (2003) NLM (1992) NLM (2003) NLM (2006) NLM (2014) |
|
| tui |
T116 T123 T121 |
|
| subClassOf |