loading...| Preferred Name |
Imatinib Mesylate |
|
| Synonyms |
Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide |
|
| Definitions |
A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000068877 |
|
| altLabel |
Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide CGP 57148 ST1571 Mesylate, Imatinib Imatinib Methanesulfonate Glivec Methanesulfonate, Imatinib Gleevec STI-571 CGP-57148 STI 571 CGP57148B CGP57148 Imatinib ST 1571 STI571 |
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C0939537 C0385728 C0935989 C0935987 C0906802 C1097576 |
|
| DC |
1 |
|
| definition |
A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors. |
|
| DX |
20160101 |
|
| HN |
2016 (1996) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
8A1O1M485B BKJ8M8G5HI 0 |
|
| isa | ||
| LT |
TRD |
|
| Machine permutation |
2016; IMATINIB MESYLATE was indexed under BENZAMIDES, PIPERAZINES, and PYRIMIDINES 1996-2015 |
|
| MDA |
20150709 |
|
| MMR |
20160531 |
|
| MN |
D02.241.223.100.100.435 D03.383.606.405 D03.383.742.349 D02.065.277.456 D02.455.426.559.389.127.085.465 |
|
| notation |
D000068877 |
|
| PA |
D047428 D000970 |
|
| prefLabel |
Imatinib Mesylate |
|
| RR |
220127-57-1 (imatinib mesilate) BKJ8M8G5HI |
|
| TERMUI |
T000877621 T464315 T286582 T422230 T464316 T000877618 T415637 T422611 T422231 T000877622 T454053 T453015 T286583 T000877623 |
|
| TH |
NLM (1996) US NLM (2002) MX UK NLM (2000) CA FDA SRS (2013) NLM (2001) USAN (19XX) INN (19XX) NLM (2013) DE NLM (2014) FR |
|
| tui |
T109 T121 |
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D011743 |