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Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D016472
http://purl.bioontology.org/ontology/MESH/D016472
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|---|---|
| Preferred Name | Motor Neuron Disease |
| Definitions |
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
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| Synonyms |
Familial Motor Neuron Disease
Sclerosis, Primary Lateral
Motor Neuron Diseases
Motor System Diseases
Primary Lateral Sclerosis
Motor Neuron Disease, Lower
Scleroses, Lateral
Lateral Scleroses
Primary Lateral Scleroses
Lateral Sclerosis, Primary
Neuron Disease, Motor
Secondary Motor Neuron Disease
Neuron Diseases, Motor
Upper Motor Neuron Disease
Motor Neuron Disease, Familial
Motor System Disease
Motor Neuron Disease, Secondary
Lateral Scleroses, Primary
Scleroses, Primary Lateral
Lower Motor Neuron Disease
Motor Neuron Disease, Upper
Anterior Horn Cell Disease
Lateral Sclerosis
Sclerosis, Lateral
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) |
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| altLabel |
Familial Motor Neuron Disease
Sclerosis, Primary Lateral
Motor Neuron Diseases
Motor System Diseases
Primary Lateral Sclerosis
Motor Neuron Disease, Lower
Scleroses, Lateral
Lateral Scleroses
Primary Lateral Scleroses
Lateral Sclerosis, Primary
Neuron Disease, Motor
Secondary Motor Neuron Disease
Neuron Diseases, Motor
Upper Motor Neuron Disease
Motor Neuron Disease, Familial
Motor System Disease
Motor Neuron Disease, Secondary
Lateral Scleroses, Primary
Scleroses, Primary Lateral
Lower Motor Neuron Disease
Motor Neuron Disease, Upper
Anterior Horn Cell Disease
Lateral Sclerosis
Sclerosis, Lateral
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| prefLabel | Motor Neuron Disease
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| TH |
NLM (2000)
NLM (1992)
UNK (19XX)
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| notation | D016472
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| DX | 19920101
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| Machine permutation | 92
|
| MN |
C10.574.562
C10.668.467
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| MMR | 20100625
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| Mapped from | |
| AQL | BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI
|
| HN | 92
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| subClassOf | |
| Semantic type UMLS property | |
| DC | 1
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| MDA | 19910621
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| Inverse of RO | |
| type | |
| tui | T047
|
| cui |
C0154681
C0270763
C0085084
C0154682
C0270764
C0521659
C0543858
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| AN | general or unspecified; prefer specifics
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| Inverse of AQ |
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| TERMUI |
T372117
T002093
T372128
T372119
T372125
T372127
T372130
T372129
T049287
T372123
T372118
T372126
T372124
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