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Medical Subject Headings
Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D010300
http://purl.bioontology.org/ontology/MESH/D010300
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|---|---|
| Preferred Name | Parkinson Disease |
| Definitions |
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
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| Synonyms |
Idiopathic Parkinson's Disease
Lewy Body Parkinson Disease
Paralysis Agitans
Primary Parkinsonism
Parkinson's Disease
Parkinson's Disease, Lewy Body
Parkinsonism, Primary
Idiopathic Parkinson Disease
Parkinson Disease, Idiopathic
Lewy Body Parkinson's Disease
Parkinson's Disease, Idiopathic
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) |
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| altLabel |
Idiopathic Parkinson's Disease
Lewy Body Parkinson Disease
Paralysis Agitans
Primary Parkinsonism
Parkinson's Disease
Parkinson's Disease, Lewy Body
Parkinsonism, Primary
Idiopathic Parkinson Disease
Parkinson Disease, Idiopathic
Lewy Body Parkinson's Disease
Parkinson's Disease, Idiopathic
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| prefLabel | Parkinson Disease
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| TH |
OMIM (2013)
NLM (2000)
NLM (1992)
UNK (19XX)
GHR (2014)
NLM (1967)
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| notation | D010300
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| EC | chemically induced:Parkinson Disease, Secondary/chemically induced
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| DX | 19670101
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| Machine permutation | 1979; see PARKINSONISM 1967-1978, see PARALYSIS AGITANS 1963-1966
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| MN |
C10.574.928.750
C10.228.662.600.400
C10.228.140.079.862.500
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| FX | D016631
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| MMR | 20190521
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| Mapped from |
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| AQL | BL CF CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI
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| HN | 1979(1963)
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| subClassOf | |
| Semantic type UMLS property | |
| DC | 1
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| MDA | 19990101
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| Inverse of RO | |
| type | |
| tui | T047
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| cui | C0030567
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| AN | /chem ind = PARKINSON DISEASE, SECONDARY /chem ind
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| Inverse of AQ |
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| TERMUI |
T030419
T030420
T364509
T364507
T364508
T364512
T364511
T364510
T030418
T364505
T364506
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