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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D064246
http://purl.bioontology.org/ontology/MESH/D064246
|
|---|---|
| Preferred Name | Mad2 Proteins |
| Definitions |
Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES.
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| Synonyms |
Mad2 Mitotic Arrest Deficient-like 1 Proteins
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES. |
|---|---|
| altLabel | Mad2 Mitotic Arrest Deficient-like 1 Proteins
|
| prefLabel | Mad2 Proteins
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| Machine permutation | 2014; was indexed under CELL CYCLE PROTEINS 2000-2013 and NUCLEAR PROTEINS 2005-2013
|
| HN | 2014
|
| Mapped from |
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| type | |
| tui |
T116
T123
|
| TERMUI |
T836050
T836742
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| TH | NLM (2014)
|
| MMR | 20140101
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| notation | D064246
|
| Semantic type UMLS property | |
| Inverse of AQ |
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|
| DX | 20140101
|
| cui | C3658249
|
| DC | 1
|
| MN |
D12.776.660.526
D12.776.167.313
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| AQL | AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
| Inverse of RB | 0
|
| MDA | 20130122
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |