Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D064007
http://purl.bioontology.org/ontology/MESH/D064007
Preferred Name

Ataxia Telangiectasia Mutated Proteins

Definitions
A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.
Synonyms
Protein, A-T
ATM Protein
Protein, AT Mutated
A T Protein
Mutated Protein, AT
AT Mutated Protein
A-T Protein
Type http://www.w3.org/2002/07/owl#Class
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