Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D060746
http://purl.bioontology.org/ontology/MESH/D060746
Preferred Name

Endoplasmic Reticulum-Associated Degradation

Definitions
A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.
Synonyms
Pathways, ERAD
ERAD Pathways
Endoplasmic Reticulum Associated Degradation
ERAD Pathway
Reticulum-Associated Degradation, Endoplasmic
Degradation, Endoplasmic Reticulum-Associated
Pathway, ERAD
Type http://www.w3.org/2002/07/owl#Class
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