Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D059004 http://purl.bioontology.org/ontology/MESH/D059004
Preferred Name	Topoisomerase I Inhibitors
Definitions	Compounds that inhibit the activity of DNA TOPOISOMERASE I.
Synonyms	I Inhibitor, Topoisomerase Topoisomerase 3 Inhibitors DNA Type III Topoisomerase Inhibitors Inhibitors, Topoisomerase 3 DNA Type III Topoisomerase Inhibitor Topoisomerase I Inhibitor 3 Inhibitors, Topoisomerase 1 Inhibitor, Topoisomerase 3 Inhibitor, Topoisomerase Inhibitor, Topoisomerase 3 DNA Topoisomerase I Inhibitors Topoisomerase 1 Inhibitors DNA Topoisomerase III Inhibitor DNA Type 1 Topoisomerase Inhibitors Inhibitor, Topoisomerase 1 III Inhibitor, Topoisomerase Topoisomerase III Inhibitor Inhibitors, Topoisomerase III DNA Type 1 Topoisomerase Inhibitor DNA Topoisomerase III Inhibitors III Inhibitors, Topoisomerase Inhibitor, Topoisomerase I Topoisomerase 3 Inhibitor Inhibitors, Topoisomerase 1 Inhibitor, Topoisomerase III Topoisomerase 1 Inhibitor Topoisomerase III Inhibitors DNA Topoisomerase I Inhibitor Inhibitors, Topoisomerase I See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	Compounds that inhibit the activity of DNA TOPOISOMERASE I.
altLabel	I Inhibitor, Topoisomerase Topoisomerase 3 Inhibitors DNA Type III Topoisomerase Inhibitors Inhibitors, Topoisomerase 3 DNA Type III Topoisomerase Inhibitor Topoisomerase I Inhibitor 3 Inhibitors, Topoisomerase 1 Inhibitor, Topoisomerase 3 Inhibitor, Topoisomerase Inhibitor, Topoisomerase 3 DNA Topoisomerase I Inhibitors Topoisomerase 1 Inhibitors DNA Topoisomerase III Inhibitor DNA Type 1 Topoisomerase Inhibitors Inhibitor, Topoisomerase 1 III Inhibitor, Topoisomerase Topoisomerase III Inhibitor Inhibitors, Topoisomerase III DNA Type 1 Topoisomerase Inhibitor DNA Topoisomerase III Inhibitors III Inhibitors, Topoisomerase Inhibitor, Topoisomerase I Topoisomerase 3 Inhibitor Inhibitors, Topoisomerase 1 Inhibitor, Topoisomerase III Topoisomerase 1 Inhibitor Topoisomerase III Inhibitors DNA Topoisomerase I Inhibitor Inhibitors, Topoisomerase I See more See less
prefLabel	Topoisomerase I Inhibitors
Machine permutation	2011
HN	2011
type	http://www.w3.org/2002/07/owl#Class
tui	T121
TERMUI	T000997164 T000997169 T769945 T769944 T000997167 T000997166 T000958398 T769946 T000997165 T000958399 T000958400 T769956 T000958397 T000997168 T000997170 T000998196 See more See less
TH	NLM (2020) NLM (2021) NLM (2011)
MMR	20200527
notation	D059004
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T121
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	20110101
cui	C0594374 C5197869
DC	1
MN	D27.505.519.389.892.500 D27.505.954.248.794.500
AQL	AD AE AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
Inverse of RB	0
Inverse of isa	http://purl.bioontology.org/ontology/MESH/C036411 http://purl.bioontology.org/ontology/MESH/C522460 http://purl.bioontology.org/ontology/MESH/C513777 http://purl.bioontology.org/ontology/MESH/C112865 http://purl.bioontology.org/ontology/MESH/C502983 http://purl.bioontology.org/ontology/MESH/C488364 http://purl.bioontology.org/ontology/MESH/C488183 http://purl.bioontology.org/ontology/MESH/C406631 http://purl.bioontology.org/ontology/MESH/D000077146 http://purl.bioontology.org/ontology/MESH/C530146 http://purl.bioontology.org/ontology/MESH/C530145 http://purl.bioontology.org/ontology/MESH/C095887 http://purl.bioontology.org/ontology/MESH/C402784 http://purl.bioontology.org/ontology/MESH/C091114 http://purl.bioontology.org/ontology/MESH/C091115 http://purl.bioontology.org/ontology/MESH/C091116 http://purl.bioontology.org/ontology/MESH/C515731 http://purl.bioontology.org/ontology/MESH/C515730 http://purl.bioontology.org/ontology/MESH/C548684 http://purl.bioontology.org/ontology/MESH/C544233 http://purl.bioontology.org/ontology/MESH/C088528 http://purl.bioontology.org/ontology/MESH/C088527 http://purl.bioontology.org/ontology/MESH/C103388 http://purl.bioontology.org/ontology/MESH/C066731 http://purl.bioontology.org/ontology/MESH/C095704 http://purl.bioontology.org/ontology/MESH/C116963 http://purl.bioontology.org/ontology/MESH/C079905 http://purl.bioontology.org/ontology/MESH/C510007 http://purl.bioontology.org/ontology/MESH/C063442 http://purl.bioontology.org/ontology/MESH/C063444 http://purl.bioontology.org/ontology/MESH/C063443 http://purl.bioontology.org/ontology/MESH/D002166 http://purl.bioontology.org/ontology/MESH/C543501 http://purl.bioontology.org/ontology/MESH/C070538 http://purl.bioontology.org/ontology/MESH/C550937 http://purl.bioontology.org/ontology/MESH/C417103 http://purl.bioontology.org/ontology/MESH/C417102 http://purl.bioontology.org/ontology/MESH/C417105 http://purl.bioontology.org/ontology/MESH/C417104 http://purl.bioontology.org/ontology/MESH/C116935 http://purl.bioontology.org/ontology/MESH/C409448 http://purl.bioontology.org/ontology/MESH/C409447 http://purl.bioontology.org/ontology/MESH/C000717675 http://purl.bioontology.org/ontology/MESH/C421503 http://purl.bioontology.org/ontology/MESH/C117812 http://purl.bioontology.org/ontology/MESH/C117811 http://purl.bioontology.org/ontology/MESH/C404513 http://purl.bioontology.org/ontology/MESH/C120068 http://purl.bioontology.org/ontology/MESH/C120069 http://purl.bioontology.org/ontology/MESH/C528794 http://purl.bioontology.org/ontology/MESH/C116718 http://purl.bioontology.org/ontology/MESH/C446952 http://purl.bioontology.org/ontology/MESH/C119214 http://purl.bioontology.org/ontology/MESH/D019772 http://purl.bioontology.org/ontology/MESH/C117791 http://purl.bioontology.org/ontology/MESH/C533991 http://purl.bioontology.org/ontology/MESH/C439974 http://purl.bioontology.org/ontology/MESH/C415158 http://purl.bioontology.org/ontology/MESH/C076178 http://purl.bioontology.org/ontology/MESH/C098365 http://purl.bioontology.org/ontology/MESH/C098366 http://purl.bioontology.org/ontology/MESH/C106647 http://purl.bioontology.org/ontology/MESH/C507012 http://purl.bioontology.org/ontology/MESH/C507013 See more See less
MDA	20100421
subClassOf	http://purl.bioontology.org/ontology/MESH/D059003

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display