Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D056769
http://purl.bioontology.org/ontology/MESH/D056769
Preferred Name

Alstrom Syndrome

Definitions
Rare autosomal recessive disease characterized by multiple organ dysfunction. The key clinical features include retinal degeneration (NYSTAGMUS, PATHOLOGIC; RETINITIS PIGMENTOSA; and eventual blindness), childhood obesity, sensorineural hearing loss, and normal mental development. Endocrinologic complications include TYPE 2 DIABETES MELLITUS; HYPERINSULINEMIA; ACANTHOSIS NIGRICANS; HYPOTHYROIDISM; and progressive renal and hepatic failures. The disease is caused by mutations in the ALMS1 gene.
Synonyms
Syndrome, Alstrom
Alstrom Hallgren Syndrome
Syndrome, Alström
Syndrome, Alstrom-Hallgren
Alstroms Syndrome
Syndrome, Alstrom's
Alstrom-Hallgren Syndrome
Alström Syndrome
Alstrom's Syndrome
Type http://www.w3.org/2002/07/owl#Class
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