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Medical Subject Headings
| Preferred Name | Transforming Growth Factor beta1 | |
| Synonyms |
TGF-beta1 TGF beta1 Latency Associated Protein TGF-beta1 Latency-Associated Protein Latency-Associated Protein, TGF-beta1 TGF beta1LAP TGF-beta-1 TGF beta 1 TGF-beta1LAP Transforming Growth Factor beta 1 Latency Associated Peptide Transforming Growth Factor beta I Transforming Growth Factor-beta1 |
|
| Definitions |
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D053773 |
|
| altLabel |
TGF-beta1 TGF beta1 Latency Associated Protein TGF-beta1 Latency-Associated Protein Latency-Associated Protein, TGF-beta1 TGF beta1LAP TGF-beta-1 TGF beta 1 TGF-beta1LAP Transforming Growth Factor beta 1 Latency Associated Peptide Transforming Growth Factor beta I Transforming Growth Factor-beta1
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|
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
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|
| cui |
C0169144 C1704256
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|
| DC |
1
|
|
| definition |
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
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|
| DX |
20070101
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|
| EC |
deficiency:Camurati-Engelmann Syndrome
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|
| HN |
2007(1992)
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|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
0
|
|
| Machine permutation |
2007; TRANSFORMING GROWTH FACTOR BETA1 was indexed under TRANSFORMING GROWTH FACTOR 2000-2006; TRANSFORMING GROWTH FACTOR BETA 1 LATENCY ASSOCIATED PEPTIDE was indexed under TRANSFORMING GROWTH FACTOR 1992-2006; TRANSFORMING GROWTH FACTOR BETA I was indexed under PROTEINS 2005-2006
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| Mapped from |
http://purl.bioontology.org/ontology/MESH/C508961 http://purl.bioontology.org/ontology/MESH/C508962 http://purl.bioontology.org/ontology/MESH/C508960 http://purl.bioontology.org/ontology/MESH/C465540 |
|
| MDA |
20060705
|
|
| MMR |
20200221
|
|
| MN |
D12.776.467.374.687.100 D12.644.276.954.775.100 D12.644.276.374.687.100 D23.529.374.687.100 D23.529.942.775.100 D12.776.467.942.775.100
|
|
| notation |
D053773
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|
| prefLabel |
Transforming Growth Factor beta1
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|
| TERMUI |
T660160 T000997981 T414522 T048252 T642063 T410572 T048253 T414523
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|
| TH |
NLM (2021) NLM (2007)
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|
| tui |
T116 T123 T121
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| subClassOf |
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