Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D053200
http://purl.bioontology.org/ontology/MESH/D053200
Preferred Name

Fas-Associated Death Domain Protein

Definitions
A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.
Synonyms
FADD Protein, Fas Associating
Fas-Associating Protein FADD
Fas-Associating Protein with Death Domain
Fas Associated Death Domain Protein
FADD, Fas-Associating Protein
Fas-Associating FADD Protein
Fas Associating Protein FADD
Fas Associating Protein with Death Domain
MORT1 Protein
FADD Protein, Fas-Associating
Type http://www.w3.org/2002/07/owl#Class
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