Medical Subject Headings

Last uploaded: August 28, 2024
Preferred Name

Cyclin-Dependent Kinase 4
Synonyms

Cyclin D-Dependent Kinase CDK4

p34PSK J3 Kinase

p34PSK-J3 Kinase

Cell Division Protein Kinase 4

Protein Kinase, Cdk4

Cdk4 Cyclin-Dependent Kinase

Cdk4 Protein

Cyclin Dependent Kinase 4

PSK-J3 Kinase

Cyclin-Dependent Kinase, Cdk4

Cdk4 Cyclin Dependent Kinase

Cyclin D Dependent Kinase CDK4

PSK J3 Kinase

Cdk4 Protein Kinase

Definitions

Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.

ID

http://purl.bioontology.org/ontology/MESH/D051358

altLabel

Cyclin D-Dependent Kinase CDK4

p34PSK J3 Kinase

p34PSK-J3 Kinase

Cell Division Protein Kinase 4

Protein Kinase, Cdk4

Cdk4 Cyclin-Dependent Kinase

Cdk4 Protein

Cyclin Dependent Kinase 4

PSK-J3 Kinase

Cyclin-Dependent Kinase, Cdk4

Cdk4 Cyclin Dependent Kinase

Cyclin D Dependent Kinase CDK4

PSK J3 Kinase

Cdk4 Protein Kinase

AQL

AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR

cui

C0246957

DC

1

definition

Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.

DX

20060101

HN

2006(1992)

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000096

http://purl.bioontology.org/ontology/MESH/Q000172

http://purl.bioontology.org/ontology/MESH/Q000627

http://purl.bioontology.org/ontology/MESH/Q000648

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000187

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000528

Inverse of RB

EC 2.7.11.22

Machine permutation

2006; CYCLIN-DEPENDENT KINASE 4 was indexed under CYCLIN-DEPENDENT KINASES & PROTO-ONCOGENE PROTEINS 2005, CELL CYCLE PROTEINS 1992-2004, PROTEIN SERINE THREONINE KINASES 1995, & under PROTEIN KINASES 1992-1994

Mapped from

http://purl.bioontology.org/ontology/MESH/C495899

http://purl.bioontology.org/ontology/MESH/C495896

http://purl.bioontology.org/ontology/MESH/C495902

http://purl.bioontology.org/ontology/MESH/C495900

http://purl.bioontology.org/ontology/MESH/C495903

MDA

20050630

MMR

20210521

MN

D12.776.476.563.646.500.875

D12.776.167.200.451

D08.811.913.696.620.682.700.646.500.875

notation

D051358

prefLabel

Cyclin-Dependent Kinase 4

TERMUI

T238275

T238277

T238279

T238278

T238282

T238276

T613733

T634007

TH

NLM (2006)

tui

T116

T129

T126

subClassOf

http://purl.bioontology.org/ontology/MESH/D018844

Delete Subject Author Type Created
No notes to display
Create mapping

Mapping To Ontology Source
http://purl.bioontology.org/ontology/LNC/MTHU065259 LOINC CUI
http://purl.bioontology.org/ontology/MSHFRE/D051358 MSHFRE CUI
http://purl.bioontology.org/ontology/NDFRT/N0000170542 NDFRT CUI
http://purl.bioontology.org/ontology/LNC/LP420965-8 LOINC CUI
http://purl.bioontology.org/ontology/CSP/4008-0030 CRISP CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000257373 PDQ CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.360.250.451 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.476.250.451 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.167.200.451 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU065259 LOINC LOOM
http://id.nlm.nih.gov/mesh/D051358 MDM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17680 NCIT LOOM
http://www.orpha.net/ORDO/Orphanet_119289 ORDO LOOM
http://www.drugtargetontology.org/dto/DTO_03100070 DTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D051358 RH-MESH LOOM
http://purl.jp/bio/4/id/200906080438794425 IOBC LOOM
http://purl.obolibrary.org/obo/NCIT_C17680 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.913.696.620.682.700.646.500.875 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D051358 BERO LOOM
http://purl.bioontology.org/ontology/LNC/LP420965-8 LOINC LOOM
http://purl.bioontology.org/ontology/OMIM/123829 OMIM LOOM
http://purl.obolibrary.org/obo/OMIT_0024801 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.913.696.620.682.700.200.451 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00020649 PMAPP-PMO LOOM
http://www.limics.org/hrdo/rdfns#gen_id_15422 HRDO LOOM