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Medical Subject Headings
Preferred Name | Cyclin-Dependent Kinase 4 | |
Synonyms |
Cyclin D-Dependent Kinase CDK4 p34PSK J3 Kinase p34PSK-J3 Kinase Cell Division Protein Kinase 4 Protein Kinase, Cdk4 Cdk4 Cyclin-Dependent Kinase Cdk4 Protein Cyclin Dependent Kinase 4 PSK-J3 Kinase Cyclin-Dependent Kinase, Cdk4 Cdk4 Cyclin Dependent Kinase Cyclin D Dependent Kinase CDK4 PSK J3 Kinase Cdk4 Protein Kinase |
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Definitions |
Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16. |
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ID |
http://purl.bioontology.org/ontology/MESH/D051358 |
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altLabel |
Cyclin D-Dependent Kinase CDK4 p34PSK J3 Kinase p34PSK-J3 Kinase Cell Division Protein Kinase 4 Protein Kinase, Cdk4 Cdk4 Cyclin-Dependent Kinase Cdk4 Protein Cyclin Dependent Kinase 4 PSK-J3 Kinase Cyclin-Dependent Kinase, Cdk4 Cdk4 Cyclin Dependent Kinase Cyclin D Dependent Kinase CDK4 PSK J3 Kinase Cdk4 Protein Kinase
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AQL |
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
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cui |
C0246957
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DC |
1
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definition |
Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.
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DX |
20060101
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HN |
2006(1992)
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Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
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Inverse of RB |
EC 2.7.11.22
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Machine permutation |
2006; CYCLIN-DEPENDENT KINASE 4 was indexed under CYCLIN-DEPENDENT KINASES & PROTO-ONCOGENE PROTEINS 2005, CELL CYCLE PROTEINS 1992-2004, PROTEIN SERINE THREONINE KINASES 1995, & under PROTEIN KINASES 1992-1994
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Mapped from |
http://purl.bioontology.org/ontology/MESH/C495899 http://purl.bioontology.org/ontology/MESH/C495896 http://purl.bioontology.org/ontology/MESH/C495902 |
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MDA |
20050630
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MMR |
20210521
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MN |
D12.776.476.563.646.500.875 D12.776.167.200.451 D08.811.913.696.620.682.700.646.500.875
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notation |
D051358
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prefLabel |
Cyclin-Dependent Kinase 4
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TERMUI |
T238275 T238277 T238279 T238278 T238282 T238276 T613733 T634007
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TH |
NLM (2006)
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tui |
T116 T129 T126
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subClassOf |
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