Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D051102 http://purl.bioontology.org/ontology/MESH/D051102
Preferred Name	Serine C-Palmitoyltransferase
Definitions	A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.
Synonyms	Palmitoyltransferase, Serine Long Chain Base Biosynthesis Protein 2 Serine Palmitoyltransferase 1 Palmitoyltransferase 2, Serine Palmitoyltransferase 1, Serine Palmitoyl-CoA-L-Serine C-Palmitoyltransferase (Decarboxylating) Transferase 2, Serine-Palmitoyl-CoA Serine Palmitoyltransferase, Long Chain Base Subunit 1 Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating) Long Chain Base Biosynthesis Protein 1 Serine C Palmitoyltransferase Serine-Palmitoyl-CoA Transferase 2 Serine Palmitoyltransferase, Long Chain Base Subunit 2 Serine Palmitoyl CoA Transferase 2 Serine Palmitoyltransferase Serine Palmitoyltransferase 2 C-Palmitoyltransferase, Serine See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.
altLabel	Palmitoyltransferase, Serine Long Chain Base Biosynthesis Protein 2 Serine Palmitoyltransferase 1 Palmitoyltransferase 2, Serine Palmitoyltransferase 1, Serine Palmitoyl-CoA-L-Serine C-Palmitoyltransferase (Decarboxylating) Transferase 2, Serine-Palmitoyl-CoA Serine Palmitoyltransferase, Long Chain Base Subunit 1 Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating) Long Chain Base Biosynthesis Protein 1 Serine C Palmitoyltransferase Serine-Palmitoyl-CoA Transferase 2 Serine Palmitoyltransferase, Long Chain Base Subunit 2 Serine Palmitoyl CoA Transferase 2 Serine Palmitoyltransferase Serine Palmitoyltransferase 2 C-Palmitoyltransferase, Serine See more See less
prefLabel	Serine C-Palmitoyltransferase
Machine permutation	2006; SERINE C-PALMITOYLTRANSFERASE was indexed under ACYLTRANSFERASES 1984-2005
HN	2006(1984)
Mapped from	http://purl.bioontology.org/ontology/MESH/C582181 http://purl.bioontology.org/ontology/MESH/C541445 http://purl.bioontology.org/ontology/MESH/C500534 http://purl.bioontology.org/ontology/MESH/C495090 http://purl.bioontology.org/ontology/MESH/C495089 http://purl.bioontology.org/ontology/MESH/C495086 http://purl.bioontology.org/ontology/MESH/C495087 http://purl.bioontology.org/ontology/MESH/C495088 http://purl.bioontology.org/ontology/MESH/C487784 http://purl.bioontology.org/ontology/MESH/C530166 http://purl.bioontology.org/ontology/MESH/C521151 http://purl.bioontology.org/ontology/MESH/C518504 See more See less
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T126
TERMUI	T627714 T627718 T149854 T627716 T149852 T149853 T627715 T627719 T627691 T627713 T627717 See more See less
TH	NLM (2006)
MMR	20060101
notation	D051102
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T126 http://purl.bioontology.org/ontology/STY/T116
RR	EC 2.3.1.50
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	20060101
cui	C0074375 C1531048 C1531049
DC	1
MN	D08.811.913.050.668
AQL	AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
Inverse of RB	EC 2.3.1.50
MDA	20050112
subClassOf	http://purl.bioontology.org/ontology/MESH/D000217

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