Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D050600 http://purl.bioontology.org/ontology/MESH/D050600
Preferred Name	SNARE Proteins
Definitions	A superfamily of small proteins which are involved in the MEMBRANE FUSION events, intracellular protein trafficking and secretory processes. They share a homologous SNARE motif. The SNARE proteins are divided into subfamilies: QA-SNARES; QB-SNARES; QC-SNARES; and R-SNARES. The formation of a SNARE complex (composed of one each of the four different types SNARE domains (Qa, Qb, Qc, and R)) mediates MEMBRANE FUSION. Following membrane fusion SNARE complexes are dissociated by the NSFs (N-ETHYLMALEIMIDE-SENSITIVE FACTORS), in conjunction with SOLUBLE NSF ATTACHMENT PROTEIN, i.e., SNAPs (no relation to SNAP 25.)
Synonyms	t-SNARE SNARE Proteins, Target NSF Attachment Protein Receptor Soluble N ethylmaleimide Sensitive Factor Attachment Protein Receptor Receptor, SNAP SNAP Receptors SNARE SNARE Proteins, Vesicular Soluble N-ethylmaleimide-Sensitive-Factor Attachment Protein Receptor SNAREs v-SNARE tSNAREs v-SNAREs Target SNARE Proteins SNARE Proteins, Vesicle Protein, SNARE Vesicle SNARE Proteins SNARE Protein Vesicular SNARE Proteins v SNAREs SNAP Receptor Target Membrane SNARE Proteins See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	A superfamily of small proteins which are involved in the MEMBRANE FUSION events, intracellular protein trafficking and secretory processes. They share a homologous SNARE motif. The SNARE proteins are divided into subfamilies: QA-SNARES; QB-SNARES; QC-SNARES; and R-SNARES. The formation of a SNARE complex (composed of one each of the four different types SNARE domains (Qa, Qb, Qc, and R)) mediates MEMBRANE FUSION. Following membrane fusion SNARE complexes are dissociated by the NSFs (N-ETHYLMALEIMIDE-SENSITIVE FACTORS), in conjunction with SOLUBLE NSF ATTACHMENT PROTEIN, i.e., SNAPs (no relation to SNAP 25.)
altLabel	t-SNARE SNARE Proteins, Target NSF Attachment Protein Receptor Soluble N ethylmaleimide Sensitive Factor Attachment Protein Receptor Receptor, SNAP SNAP Receptors SNARE SNARE Proteins, Vesicular Soluble N-ethylmaleimide-Sensitive-Factor Attachment Protein Receptor SNAREs v-SNARE tSNAREs v-SNAREs Target SNARE Proteins SNARE Proteins, Vesicle Protein, SNARE Vesicle SNARE Proteins SNARE Protein Vesicular SNARE Proteins v SNAREs SNAP Receptor Target Membrane SNARE Proteins See more See less
prefLabel	SNARE Proteins
Machine permutation	2006; SNAP RECEPTOR (now SNARE PROTEINS) was indexed under MEMBRANE PROTEINS 1995-2003 and VESICULAR TRANSPORT PROTEINS 2004-2005
HN	2006 (1995)
Mapped from	http://purl.bioontology.org/ontology/MESH/C545213 http://purl.bioontology.org/ontology/MESH/C582513 http://purl.bioontology.org/ontology/MESH/C582206 http://purl.bioontology.org/ontology/MESH/C000622350 http://purl.bioontology.org/ontology/MESH/C539363 http://purl.bioontology.org/ontology/MESH/C585280 http://purl.bioontology.org/ontology/MESH/C574544 http://purl.bioontology.org/ontology/MESH/C000605008 http://purl.bioontology.org/ontology/MESH/C559856 http://purl.bioontology.org/ontology/MESH/C490973 http://purl.bioontology.org/ontology/MESH/C000598693 http://purl.bioontology.org/ontology/MESH/C521756 http://purl.bioontology.org/ontology/MESH/C570435 http://purl.bioontology.org/ontology/MESH/C107845 See more See less
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T192
TERMUI	T280564 T608752 T608746 T280561 T608748 T626441 T280563 T608747 T608750 T608749 T280565 T001010395 T608753 T608751 T626440 T280562 T620724 See more See less
TH	NLM (2021) NLM (2006)
MMR	20200527
notation	D050600
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T116 http://purl.bioontology.org/ontology/STY/T192
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	20060101
cui	C1506158 C1506159 C0300824
DC	1
MN	D12.776.543.512.249 D12.776.543.990.775
AQL	AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
Inverse of RB	0
MDA	20041130
subClassOf	http://purl.bioontology.org/ontology/MESH/D033921 http://purl.bioontology.org/ontology/MESH/D050576

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