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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D050051
http://purl.bioontology.org/ontology/MESH/D050051
|
|---|---|
| Preferred Name | Transient Receptor Potential Channels |
| Definitions |
A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.
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| Synonyms |
Channels, TRP Cation
Cation Channel, TRP
Membrane Proteins, TRP
Transient Receptor Potential Cation Channel
Transient Receptor Potential Cation Channels
Proteins, TRP Membrane
Cation Channels, TRP
Transient Receptor Potential Channel
TRP Membrane Proteins
TRP Cation Channel
Channel, TRP Cation
TRP Cation Channels
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES. |
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| altLabel |
Channels, TRP Cation
Cation Channel, TRP
Membrane Proteins, TRP
Transient Receptor Potential Cation Channel
Transient Receptor Potential Cation Channels
Proteins, TRP Membrane
Cation Channels, TRP
Transient Receptor Potential Channel
TRP Membrane Proteins
TRP Cation Channel
Channel, TRP Cation
TRP Cation Channels
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| prefLabel | Transient Receptor Potential Channels
|
| Machine permutation | 2006
|
| HN | 2006
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| Mapped from |
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| type | |
| tui |
T116
T123
|
| TERMUI |
T000996787
T000996785
T608887
T000996786
T000894415
T608889
T608888
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| TH |
NLM (2021)
NLM (2006)
NLM (2017)
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| MMR | 20200527
|
| notation | D050051
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| Semantic type UMLS property | |
| Inverse of AQ |
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| DX | 20060101
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| cui | C1563722
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| DC | 1
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| MN |
D12.776.543.585.400.901
D12.776.157.530.400.901
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| AN | note entry terms: TRP refers to transient receptor potential not TRYPTOPHAN
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| AQL | AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
| Inverse of RB | 0
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| MDA | 20040910
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |