Medical Subject Headings

Last uploaded: August 28, 2024

Preferred Name	Mitogen-Activated Protein Kinase 14
Synonyms	p38alpha Mitogen Activated Protein Kinase MAPK14 Mitogen-Activated Protein Kinase Cytokine Suppressive Anti-inflammatory Drug Binding Protein CSBP, Kinase Mxi2 Protein Kinase CSBP p38alpha MAP Kinase CSAID Binding Protein p38alpha Mitogen-Activated Protein Kinase MAX-Interacting Protein 2 SAPK2a p38alphaMAPK CSAID-Binding Protein MAX Interacting Protein 2 MAP Kinase, p38alpha Stress activated protein kinase 2a Mitogen Activated Protein Kinase 14 MAPK14 Mitogen Activated Protein Kinase Stress-activated protein kinase 2a Cytokine Suppressive Anti inflammatory Drug Binding Protein MAPK14
Definitions	A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580.
ID	http://purl.bioontology.org/ontology/MESH/D048308
altLabel	p38alpha Mitogen Activated Protein Kinase MAPK14 Mitogen-Activated Protein Kinase Cytokine Suppressive Anti-inflammatory Drug Binding Protein CSBP, Kinase Mxi2 Protein Kinase CSBP p38alpha MAP Kinase CSAID Binding Protein p38alpha Mitogen-Activated Protein Kinase MAX-Interacting Protein 2 SAPK2a p38alphaMAPK CSAID-Binding Protein MAX Interacting Protein 2 MAP Kinase, p38alpha Stress activated protein kinase 2a Mitogen Activated Protein Kinase 14 MAPK14 Mitogen Activated Protein Kinase Stress-activated protein kinase 2a Cytokine Suppressive Anti inflammatory Drug Binding Protein MAPK14
AQL	AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C0257535
DC	1
definition	A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580.
DX	20050101
HN	2005(1994)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	EC 2.7.11.24
Machine permutation	2005; MITOGEN-ACTIVATED PROTEIN KINASE 14 was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2002-2004; CSAID-BINDING PROTEIN & KINASE CSBP were indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2000-2004; MXI2 PROTEIN was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2000-2004, under CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-2000
MDA	20040707
MMR	20210521
MN	D12.776.476.563.567.843.937 D08.811.913.696.620.682.700.567.843.937
notation	D048308
prefLabel	Mitogen-Activated Protein Kinase 14
TERMUI	T574122 T573616 T414757 T573638 T485131 T573617 T573522 T414323 T573519 T573568 T573637 T485132 T264434
TH	NLM (2005)
tui	T116 T126
subClassOf	http://purl.bioontology.org/ontology/MESH/D048051

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/NDFRT/N0000170536	NDFRT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D048308	MSHFRE	CUI
http://purl.bioontology.org/ontology/LNC/MTHU019341	LOINC	CUI
http://purl.bioontology.org/ontology/LNC/LP269050-3	LOINC	CUI
http://purl.bioontology.org/ontology/OMIM/600289	OMIM	LOOM
http://purl.obolibrary.org/obo/PR_000003107	PR	LOOM
http://purl.obolibrary.org/obo/PR_000003107	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/PR_000003107	CIDO	LOOM
http://purl.obolibrary.org/obo/PR_000003107	NIFSTD	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26369	NCIT	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00020624	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/OMIT_0024042	OMIT	LOOM
http://purl.bioontology.org/ontology/LNC/LP36221-7	LOINC	LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Mitogen-Activated_Protein_Kinase_14	SEPON	LOOM
http://purl.jp/bio/4/id/200906043826851292	IOBC	LOOM
http://purl.obolibrary.org/obo/dinto_1983	DINTO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.360.450.835.800	RH-MESH	LOOM
http://www.drugtargetontology.org/dto/DTO_03100326	DTO	LOOM
http://id.nlm.nih.gov/mesh/D048308	MDM	LOOM
http://www.bioassayontology.org/bao#BAO_0002109	BAO	LOOM
http://purl.obolibrary.org/obo/MESH_D048308	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D048308	RH-MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C26369	BERO	LOOM