Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D045384 http://purl.bioontology.org/ontology/MESH/D045384
Preferred Name	Pregnancy-Associated alpha 2-Macroglobulins
Definitions	Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high concentration in the plasma of PREGNANT PEOPLE but also in a number of species including mouse, rat, and others (ALPHA-MACROGLOBULINS). In humans, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES, similar to COMPLEMENT PROTEINS (C3; C4; C5).
Synonyms	alpha 2-Macroglobulin alpha 2-Globulins, Pregnancy-Associated Pregnancy Associated alpha 2 Macroglobulins alpha 2-Glucoprotein Pregnancy-Associated alpha 2-Glycoproteins alpha2-Macroglobulin alpha 2-Glucoproteins PAAG alpha 2 Glucoproteins alpha2 Macroglobulin Pregnancy Associated alpha 2 Globulins alpha 2 Macroglobulin alpha2-PAG alpha 2 Glucoprotein Pregnancy-Associated alpha 2-Globulins Pregnancy Associated alpha 2 Glycoproteins alpha 2-Macroglobulins, Pregnancy-Associated alpha(2)-PAG alpha 2-Glycoproteins, Pregnancy-Associated alpha2 PAG See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high concentration in the plasma of PREGNANT PEOPLE but also in a number of species including mouse, rat, and others (ALPHA-MACROGLOBULINS). In humans, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES, similar to COMPLEMENT PROTEINS (C3; C4; C5).
altLabel	alpha 2-Macroglobulin alpha 2-Globulins, Pregnancy-Associated Pregnancy Associated alpha 2 Macroglobulins alpha 2-Glucoprotein Pregnancy-Associated alpha 2-Glycoproteins alpha2-Macroglobulin alpha 2-Glucoproteins PAAG alpha 2 Glucoproteins alpha2 Macroglobulin Pregnancy Associated alpha 2 Globulins alpha 2 Macroglobulin alpha2-PAG alpha 2 Glucoprotein Pregnancy-Associated alpha 2-Globulins Pregnancy Associated alpha 2 Glycoproteins alpha 2-Macroglobulins, Pregnancy-Associated alpha(2)-PAG alpha 2-Glycoproteins, Pregnancy-Associated alpha2 PAG See more See less
prefLabel	Pregnancy-Associated alpha 2-Macroglobulins
Machine permutation	2004; see PREGNANCY ZONE PROTEINS 1980-2003; for ALPHA 2-GLUCOPROTEINS see ALPHA-MACROGLOBULINS 1976-2017
HN	2018 (2004); for ALPHA 2-GLUCOPROTEINS use ALPHA-MACROGLOBULINS 1976-2017
Mapped from	http://purl.bioontology.org/ontology/MESH/C020881
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T123
TERMUI	T033194 T001502 T001503 T033193 T001505 T033196 T033197 T033198 T001504 T033200 See more See less
TH	UNK (19XX)
MMR	20240809
notation	D045384
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T123 http://purl.bioontology.org/ontology/STY/T116
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	20040101
cui	C1176473 C0002198
DC	1
MN	D12.776.124.790.720.100.500 D12.776.780.675
AQL	AD AE AG AI AN BI CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
Inverse of RB	0
MDA	19790222
subClassOf	http://purl.bioontology.org/ontology/MESH/D000511 http://purl.bioontology.org/ontology/MESH/D011257

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