Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D044843 http://purl.bioontology.org/ontology/MESH/D044843
Preferred Name	SKP Cullin F-Box Protein Ligases
Definitions	A subset of ubiquitin protein ligases that are formed by the association of a SKP DOMAIN PROTEIN, a CULLIN DOMAIN PROTEIN and a F-BOX DOMAIN PROTEIN.
Synonyms	SCF(Fbw7) Ubiquitin Ligase Skp1 Cullin F Box Proteins SKP1-Cullin Ubiquitin Ligases Ligase, Skp1-Cullin-1-F-box Ubiquitin Ubiquitin Ligases, SKP1-Cullin SCF(beta-TrCP) Ubiquitin Ligase Skp1-Cullin-F-Box Proteins SKP1 Cullin Ubiquitin Ligases Skp1-Cullin-1-F-box Ubiquitin Ligase Ligase, SCF Ubiquitin SCF Ubiquitin Ligase Skp1 Cullin 1 F box Ubiquitin Ligase Ligases, SKP1-Cullin Ubiquitin Ubiquitin Ligase, Skp1-Cullin-1-F-box SKP Cullin F Box Protein Ligases Ubiquitin Ligase, SCF See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	A subset of ubiquitin protein ligases that are formed by the association of a SKP DOMAIN PROTEIN, a CULLIN DOMAIN PROTEIN and a F-BOX DOMAIN PROTEIN.
altLabel	SCF(Fbw7) Ubiquitin Ligase Skp1 Cullin F Box Proteins SKP1-Cullin Ubiquitin Ligases Ligase, Skp1-Cullin-1-F-box Ubiquitin Ubiquitin Ligases, SKP1-Cullin SCF(beta-TrCP) Ubiquitin Ligase Skp1-Cullin-F-Box Proteins SKP1 Cullin Ubiquitin Ligases Skp1-Cullin-1-F-box Ubiquitin Ligase Ligase, SCF Ubiquitin SCF Ubiquitin Ligase Skp1 Cullin 1 F box Ubiquitin Ligase Ligases, SKP1-Cullin Ubiquitin Ubiquitin Ligase, Skp1-Cullin-1-F-box SKP Cullin F Box Protein Ligases Ubiquitin Ligase, SCF See more See less
prefLabel	SKP Cullin F-Box Protein Ligases
Machine permutation	2004; SCF UBIQUITIN LIGASE (now SKP CULLIN F-BOX LIGASES) was indexed under PEPTIDE SYNTHASES 1999-2003
HN	2004; use SKP CULLIN F-BOX LIGASES (NM) 1999-2003
Mapped from	http://purl.bioontology.org/ontology/MESH/C434749 http://purl.bioontology.org/ontology/MESH/C486692 http://purl.bioontology.org/ontology/MESH/C486691 http://purl.bioontology.org/ontology/MESH/C000607796 http://purl.bioontology.org/ontology/MESH/C440907 http://purl.bioontology.org/ontology/MESH/C449205 http://purl.bioontology.org/ontology/MESH/C484058 http://purl.bioontology.org/ontology/MESH/C485632 http://purl.bioontology.org/ontology/MESH/C504781 http://purl.bioontology.org/ontology/MESH/C584002 http://purl.bioontology.org/ontology/MESH/C120507 http://purl.bioontology.org/ontology/MESH/C000730205 http://purl.bioontology.org/ontology/MESH/C522506 http://purl.bioontology.org/ontology/MESH/C479752 See more See less
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T126
TERMUI	T533917 T332616 T332615 T467807 T533947 T534333 T419366 See more See less
TH	NLM (2004)
MMR	20160602
notation	D044843
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D044786 http://purl.bioontology.org/ontology/MESH/D044783 http://purl.bioontology.org/ontology/MESH/D044842
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T126 http://purl.bioontology.org/ontology/STY/T116
RR	EC 2.3.2.27
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
FX	D044783 D044786 D044842
DX	20040101
cui	C1257953 C1098272 C0907707 C0764911
DC	1
MN	D08.811.464.938.750.750
AQL	AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
Inverse of RB	EC 2.3.2.27
MDA	20030303
subClassOf	http://purl.bioontology.org/ontology/MESH/D044767

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