Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D044463 http://purl.bioontology.org/ontology/MESH/D044463
Preferred Name	Receptor, PAR-1
Definitions	A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.
Synonyms	Protease Activated Receptor 1 Proteinase Activated Receptor 1 Protease-Activated Receptor 1 Receptor, PAR1 Proteinase-Activated Receptor 1 PAR 1 Receptor Receptor, PAR 1 PAR1 Receptor PAR-1 Receptor
Type	http://www.w3.org/2002/07/owl#Class

definition	A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.
altLabel	Protease Activated Receptor 1 Proteinase Activated Receptor 1 Protease-Activated Receptor 1 Receptor, PAR1 Proteinase-Activated Receptor 1 PAR 1 Receptor Receptor, PAR 1 PAR1 Receptor PAR-1 Receptor See more See less
prefLabel	Receptor, PAR-1
EC	antagonists & inhibitors:Platelet Aggregation Inhibitors
Machine permutation	2004; PROTEASE-ACTIVATED RECEPTOR-1 (now RECEPTOR, PROTIENASE-ACTIVATED) was indexed under RECEPTORS, THROMBIN 1997-2003
HN	2004; use RECEPTOR, PROTEINASE-ACTIVATED 1 (NM) 1997-2003
Mapped from	http://purl.bioontology.org/ontology/MESH/C587066 http://purl.bioontology.org/ontology/MESH/C535229 http://purl.bioontology.org/ontology/MESH/C000610686
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T192
TERMUI	T313419 T313421 T313422 T313423 T313420
TH	NLM (2004)
MMR	20240809
notation	D044463
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T116 http://purl.bioontology.org/ontology/STY/T192
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	20040101
cui	C0668084
DC	1
MN	D12.776.543.750.792.500.500 D12.776.543.750.705.675.892.790 D12.776.395.550.625.800.790 D12.776.543.750.750.850.399 D09.400.430.890.625.800.790 D12.776.543.750.695.875.500 D12.776.543.550.625.800.790 See more See less
AQL	AD AG AN BI BL CH CL DE DF GE HI IM IP ME PH RE TU UL
Inverse of RB	0
MDA	19550101
subClassOf	http://purl.bioontology.org/ontology/MESH/D018179

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