Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D043524 http://purl.bioontology.org/ontology/MESH/D043524
Preferred Name	Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase
Definitions	An amidohydrolase that removes intact asparagine-linked oligosaccharide chains from glycoproteins. It requires the presence of more than two amino-acid residues in the substrate for activity. This enzyme was previously listed as EC 3.2.2.18.
Synonyms	Glycopeptidase, N-Oligosaccharide N-Oligosaccharide Glycopeptidase Peptide N-Glycanase Glycopeptidase F Peptide-N(4)-(acetyl-beta-glucosaminyl)Asparagine Amidase Peptide N-Glycosidase Peptide N Glycanase PNGase A N Glycanase Glycopeptidase A N-Glycanase N-Glycosidase, Peptide Glycopeptide N-glycosidase N Oligosaccharide Glycopeptidase N-Glycosidase A Glycopeptide N glycosidase N-Glycanase, Peptide N-glycohydrolase F, Peptide Peptide N glycohydrolase F Peptide N-glycohydrolase F Glycopeptidase PNGase F N-Glycosidase F Peptide-N-Glycanase N Glycosidase F N Glycosidase A Peptide N Glycosidase N-glycosidase, Glycopeptide See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	An amidohydrolase that removes intact asparagine-linked oligosaccharide chains from glycoproteins. It requires the presence of more than two amino-acid residues in the substrate for activity. This enzyme was previously listed as EC 3.2.2.18.
altLabel	Glycopeptidase, N-Oligosaccharide N-Oligosaccharide Glycopeptidase Peptide N-Glycanase Glycopeptidase F Peptide-N(4)-(acetyl-beta-glucosaminyl)Asparagine Amidase Peptide N-Glycosidase Peptide N Glycanase PNGase A N Glycanase Glycopeptidase A N-Glycanase N-Glycosidase, Peptide Glycopeptide N-glycosidase N Oligosaccharide Glycopeptidase N-Glycosidase A Glycopeptide N glycosidase N-Glycanase, Peptide N-glycohydrolase F, Peptide Peptide N glycohydrolase F Peptide N-glycohydrolase F Glycopeptidase PNGase F N-Glycosidase F Peptide-N-Glycanase N Glycosidase F N Glycosidase A Peptide N Glycosidase N-glycosidase, Glycopeptide See more See less
prefLabel	Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase
Machine permutation	2004; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE was indexed under AMIDOHYDROLASES 1983-2003 & GLYCOPEPTIDES 1979-1984
HN	2004; use PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE (NM) 1979 - 2003
Mapped from	http://purl.bioontology.org/ontology/MESH/C000622771 http://purl.bioontology.org/ontology/MESH/C000626124 http://purl.bioontology.org/ontology/MESH/C468820
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T126
TERMUI	T105001 T104996 T105006 T104999 T104992 T105000 T104988 T104989 T104991 T105002 T104994 T105004 T104990 T104997 T105005 T104998 See more See less
TH	NLM (2004)
MMR	20040101
notation	D043524
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T126 http://purl.bioontology.org/ontology/STY/T116
RR	EC 3.5.1.52
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	20040101
cui	C0283432 C0377091 C0061642
DC	1
MN	D08.811.277.087.725
AQL	AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
Inverse of RB	EC 3.5.1.52
MDA	19550101
subClassOf	http://purl.bioontology.org/ontology/MESH/D000581

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