loading...| Preferred Name | 1-Alkyl-2-acetylglycerophosphocholine Esterase | |
| Synonyms |
Platelet activating Factor Acetylhydrolase IB Platelet-Activating Factor Hydrolase Hydrolase, Platelet-Activating Factor Esterase, 1-Alkyl-2-acetylglycerophosphocholine Platelet Activating Factor Hydrolase PAF 2-Acylhydrolase Lp-PLA2 Lp PLA2 Factor Hydrolase, Platelet-Activating PAF 2 Acylhydrolase Lipoprotein-Associated Phospholipase A(2) Acetylhydrolase, PAF Platelet-activating Factor Acetylhydrolase IB Acetylhydrolase II, PAF 2-Acetylhydrolase, PAF PAF 2 Acetylhydrolase 1 Alkyl 2 acetylglycerophosphocholine Esterase PAF Acetylhydrolase PAF Acetylhydrolase II PAF 2-Acetylhydrolase Lipoprotein-Associated Phospholipase A2 Lp-PLA(2) Phospholipase A2, Lipoprotein-Associated Lipoprotein Associated Phospholipase A2 |
|
| Definitions |
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D043203 |
|
| altLabel |
Platelet activating Factor Acetylhydrolase IB Platelet-Activating Factor Hydrolase Hydrolase, Platelet-Activating Factor Esterase, 1-Alkyl-2-acetylglycerophosphocholine Platelet Activating Factor Hydrolase PAF 2-Acylhydrolase Lp-PLA2 Lp PLA2 Factor Hydrolase, Platelet-Activating PAF 2 Acylhydrolase Lipoprotein-Associated Phospholipase A(2) Acetylhydrolase, PAF Platelet-activating Factor Acetylhydrolase IB Acetylhydrolase II, PAF 2-Acetylhydrolase, PAF PAF 2 Acetylhydrolase 1 Alkyl 2 acetylglycerophosphocholine Esterase PAF Acetylhydrolase PAF Acetylhydrolase II PAF 2-Acetylhydrolase Lipoprotein-Associated Phospholipase A2 Lp-PLA(2) Phospholipase A2, Lipoprotein-Associated Lipoprotein Associated Phospholipase A2 |
|
| AN |
/antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS |
|
| AQL |
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C0914069 C0752903 |
|
| DC |
1 |
|
| definition |
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA. |
|
| DX |
20040101 |
|
| HN |
2004(1983) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
EC 3.1.1.47 |
|
| Machine permutation |
2004; 1-ALKYL-2-ACETYLGLYCEROLPHOSPHOCHOLINE ESTERASE was indexed under PHOSPHOLIPASES A 1983-2003; LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 was indexed under PHOSPHOLIPASES A 2000-2007 & under 1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE 2007 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C513190 http://purl.bioontology.org/ontology/MESH/C523923 http://purl.bioontology.org/ontology/MESH/C526455 http://purl.bioontology.org/ontology/MESH/C000607175 http://purl.bioontology.org/ontology/MESH/C523891 http://purl.bioontology.org/ontology/MESH/C523890 http://purl.bioontology.org/ontology/MESH/C000607176 http://purl.bioontology.org/ontology/MESH/C568468 http://purl.bioontology.org/ontology/MESH/C000622830 http://purl.bioontology.org/ontology/MESH/C571209 http://purl.bioontology.org/ontology/MESH/C566640 |
|
| MDA |
20030709 |
|
| MMR |
20130708 |
|
| MN |
D08.811.277.352.100.680.750.937.249 |
|
| notation |
D043203 |
|
| prefLabel |
1-Alkyl-2-acetylglycerophosphocholine Esterase |
|
| RR |
EC 3.1.1.47 |
|
| TERMUI |
T414161 T148405 T148403 T148410 T148407 T414164 T148406 T414162 T148404 T148408 T414163 |
|
| TH |
NLM (2004) NLM (2008) |
|
| tui |
T116 T126 |
|
| subClassOf |