Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D042782
http://purl.bioontology.org/ontology/MESH/D042782
Preferred Name

Estrogenic Steroids, Alkylated

Definitions
Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties.
Synonyms
Alkylated Estrogenic Steroids
Alkyl Estrogenic Steroids
Type http://www.w3.org/2002/07/owl#Class
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