Medical Subject Headings

Last uploaded: August 28, 2024

Preferred Name	Vascular Endothelial Growth Factor A
Synonyms	Vascular Permeability Factor Vascular Endothelial Growth Factor GD-VEGF VEGF-A Vascular Endothelial Growth Factor-A Vasculotropin VEGF Glioma Derived Vascular Endothelial Cell Growth Factor Glioma-Derived Vascular Endothelial Cell Growth Factor Permeability Factor, Vascular
Definitions	The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
ID	http://purl.bioontology.org/ontology/MESH/D042461
altLabel	Vascular Permeability Factor Vascular Endothelial Growth Factor GD-VEGF VEGF-A Vascular Endothelial Growth Factor-A Vasculotropin VEGF Glioma Derived Vascular Endothelial Cell Growth Factor Glioma-Derived Vascular Endothelial Cell Growth Factor Permeability Factor, Vascular
AQL	AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C0082709 C0078058
DC	1
definition	The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
DX	20040101
HN	2004; use VASCULAR ENDOTHELIAL GROWTH FACTOR A (NM) 2000-2002
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D016228 http://purl.bioontology.org/ontology/MESH/D000069579
Machine permutation	2004; VASCULAR ENDOTHELIAL GROWTH FACTOR was indexed under ENDOTHELIAL GROWTH FACTORS 2000-2002
Mapped from	http://purl.bioontology.org/ontology/MESH/C529227 http://purl.bioontology.org/ontology/MESH/C520135 http://purl.bioontology.org/ontology/MESH/C000630634 http://purl.bioontology.org/ontology/MESH/C467484 http://purl.bioontology.org/ontology/MESH/C467480 http://purl.bioontology.org/ontology/MESH/C519402 http://purl.bioontology.org/ontology/MESH/C511613 http://purl.bioontology.org/ontology/MESH/C583604 http://purl.bioontology.org/ontology/MESH/C579137 http://purl.bioontology.org/ontology/MESH/C467498 http://purl.bioontology.org/ontology/MESH/C000613307
MDA	20030709
MMR	20130709
MN	D12.644.276.100.800.200 D12.776.467.100.800.200 D23.529.100.800.200
notation	D042461
prefLabel	Vascular Endothelial Growth Factor A
TERMUI	T087222 T207077 T205402 T205403 T406107 T526412 T406108 T087224 T087210
TH	NLM (2004)
tui	T116 T123 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D042442

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D042461	MSHFRE	CUI
http://purl.bioontology.org/ontology/CSP/4007-0132	CRISP	CUI
http://purl.bioontology.org/ontology/LNC/LP32721-0	LOINC	CUI
http://purl.bioontology.org/ontology/LNC/MTHU048267	LOINC	CUI
http://purl.bioontology.org/ontology/CSP/4007-0132	CRISP	CUI
http://purl.bioontology.org/ontology/LNC/LP185747-5	LOINC	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000170972	NDFRT	CUI
http://purl.bioontology.org/ontology/SCTSPA/417324009	SCTSPA	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/417324009	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D042461	MSHFRE	CUI
http://purl.bioontology.org/ontology/LNC/MTHU016264	LOINC	CUI
http://purl.bioontology.org/ontology/RXNORM/2642870	RXNORM	CUI
http://purl.bioontology.org/ontology/LNC/MTHU048267	LOINC	LOOM
http://www.ncbi.nlm.nih.gov/gene/22339	NIFSTD	LOOM
http://purl.bioontology.org/ontology/LNC/LP185747-5	LOINC	LOOM
http://purl.obolibrary.org/obo/NCIT_C20450	BERO	LOOM
http://purl.obolibrary.org/obo/OMIT_0023145	OMIT	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021640	PMAPP-PMO	LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_6348191c_5c8a_4250_b394_655e59be6b09	STO-DRAFT	LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_6348191c_5c8a_4250_b394_655e59be6b09	CVAO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D042461	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D042461	BERO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20450	NCIT	LOOM
http://purl.obolibrary.org/obo/dinto_2763	DINTO	LOOM
http://purl.jp/bio/4/id/200906081728976914	IOBC	LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571347974240596174	ACVD_ONTOLOGY	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.529.100.800.200	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.467.100.800.200	RH-MESH	LOOM
http://purl.obolibrary.org/obo/PR_000017284	CIDO	LOOM
http://purl.obolibrary.org/obo/PR_000017284	NIFSTD	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.276.100.800.200	RH-MESH	LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01476	MIO	LOOM
http://purl.uniprot.org/uniprot/P15692	FTC	LOOM
http://purl.bioontology.org/ontology/OMIM/192240	OMIM	LOOM
http://scai.fraunhofer.de/CSEO#CSEO_00001109	CSEO	LOOM
http://doe-generated-ontology.com/OntoAD#C0078058	ONTOAD	LOOM