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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D037582
http://purl.bioontology.org/ontology/MESH/D037582
|
|---|---|
| Preferred Name | Complement Pathway, Mannose-Binding Lectin |
| Definitions |
Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.
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| Synonyms |
Mannose-Binding Lectin Complement Pathway
Mannan Binding Lectin Pathway (Complement Activation)
Lectin Pathways, Mannan-Binding (Complement Activation)
Mannan-Binding Lectin Complement Pathway
Mannan-Binding Lectin Pathways (Complement Activation)
Lectin Pathway, Mannan-Binding (Complement Activation)
Pathways, Lectin-Complement
Mannose Binding Lectin Complement Pathway
Pathways, Mannan-Binding Lectin (Complement Activation)
Pathway, Mannan-Binding Lectin (Complement Activation)
Lectin-Complement Pathways
Complement Pathway, Mannose Binding Lectin
Lectin Complement Pathway
Lectin-Complement Pathway
Mannan Binding Lectin Complement Pathway
Mannan-Binding Lectin Pathway (Complement Activation)
Pathway, Lectin-Complement
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX. |
|---|---|
| altLabel |
Mannose-Binding Lectin Complement Pathway
Mannan Binding Lectin Pathway (Complement Activation)
Lectin Pathways, Mannan-Binding (Complement Activation)
Mannan-Binding Lectin Complement Pathway
Mannan-Binding Lectin Pathways (Complement Activation)
Lectin Pathway, Mannan-Binding (Complement Activation)
Pathways, Lectin-Complement
Mannose Binding Lectin Complement Pathway
Pathways, Mannan-Binding Lectin (Complement Activation)
Pathway, Mannan-Binding Lectin (Complement Activation)
Lectin-Complement Pathways
Complement Pathway, Mannose Binding Lectin
Lectin Complement Pathway
Lectin-Complement Pathway
Mannan Binding Lectin Complement Pathway
Mannan-Binding Lectin Pathway (Complement Activation)
Pathway, Lectin-Complement
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| prefLabel | Complement Pathway, Mannose-Binding Lectin
|
| Machine permutation | 2003
|
| HN | 2003
|
| type | |
| tui | T044
|
| TERMUI |
T481120
T481121
T480320
T480321
T620381
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| TH |
NLM (2003)
NLM (2006)
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| MMR | 20160623
|
| notation | D037582
|
| Inverse of RO | |
| Semantic type UMLS property | |
| Inverse of AQ |
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| FX | D037601
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| DX | 20030101
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| cui | C1138407
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| DC | 1
|
| MN | G12.274.849
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| AQL | DE ES GE IM PH RE
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| MDA | 20020201
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |