Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D020897 http://purl.bioontology.org/ontology/MESH/D020897
Preferred Name	Organizers, Embryonic
Definitions	Cells in certain regions of an embryo that self-regulate embryonic development. These organizers have been found in dorsal and ventral poles of GASTRULA embryos, including Spemann organizer in amphibians, and Hensen node in chicken and mouse. These organizer cells communicate with each other via a network of secreted signaling proteins, such as BONE MORPHOGENETIC PROTEINS and their antagonists (chordin and noggin). The knot at the tip of the PRIMITIVE STREAK.
Synonyms	Embryonic Organizers Organizer, Spemann Node, Hensen's Hensen Node Embryo Organizers Hensen's Node Embryo Organizer Organizer, Spemann's Spemann's Organizer Node, Hensen Embryonic Organizer Hensens Node Spemanns Organizer Spemann Organizer Organizer, Embryonic Organizer, Embryo Organizers, Embryo See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	Cells in certain regions of an embryo that self-regulate embryonic development. These organizers have been found in dorsal and ventral poles of GASTRULA embryos, including Spemann organizer in amphibians, and Hensen node in chicken and mouse. These organizer cells communicate with each other via a network of secreted signaling proteins, such as BONE MORPHOGENETIC PROTEINS and their antagonists (chordin and noggin). The knot at the tip of the PRIMITIVE STREAK.
altLabel	Embryonic Organizers Organizer, Spemann Node, Hensen's Hensen Node Embryo Organizers Hensen's Node Embryo Organizer Organizer, Spemann's Spemann's Organizer Node, Hensen Embryonic Organizer Hensens Node Spemanns Organizer Spemann Organizer Organizer, Embryonic Organizer, Embryo Organizers, Embryo See more See less
prefLabel	Organizers, Embryonic
Machine permutation	2000
HN	2000
type	http://www.w3.org/2002/07/owl#Class
tui	T018
TERMUI	T358489 T358985 T358982 T358980 T358983 T358984 T358981 See more See less
TH	NLM (2000)
MMR	20070709
notation	D020897
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D004627
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T018
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000098 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000002 http://purl.bioontology.org/ontology/MESH/Q000033 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000254 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000294 http://purl.bioontology.org/ontology/MESH/Q000293 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000637 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000166 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
FX	D004627
DX	20000101
cui	C0752269 C0752267 C0752268
DC	1
MN	A16.675
AQL	AB AH BS CH CY DE DG EM EN GD IM IN IR ME MI PA PH PP PS RE SU TR UL VI
MDA	19991012
subClassOf	http://purl.bioontology.org/ontology/MESH/D004628

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