loading...| Preferred Name | Selective Estrogen Receptor Modulators | |
| Synonyms |
Estrogen Receptor Modulators, Selective Estrogen Receptor Modulator, Selective SERMs Selective Estrogen Receptor Modulator SERM |
|
| Definitions |
A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63) |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D020845 |
|
| altLabel |
Estrogen Receptor Modulators, Selective Estrogen Receptor Modulator, Selective SERMs Selective Estrogen Receptor Modulator SERM |
|
| AN |
do not confuse with ESTROGEN RECEPTOR MODULATORS |
|
| AQL |
AD AE AG AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C0732611 |
|
| DC |
1 |
|
| definition |
A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63) |
|
| DX |
20000101 |
|
| FX |
D050071 |
|
| HN |
2000 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of isa |
http://purl.bioontology.org/ontology/MESH/D020849 http://purl.bioontology.org/ontology/MESH/D002996 http://purl.bioontology.org/ontology/MESH/D013629 http://purl.bioontology.org/ontology/MESH/D064695 http://purl.bioontology.org/ontology/MESH/D064696 http://purl.bioontology.org/ontology/MESH/C447119 http://purl.bioontology.org/ontology/MESH/C000708173 http://purl.bioontology.org/ontology/MESH/D017312 |
|
| Inverse of RB |
0 |
|
| Inverse of RO | ||
| Machine permutation |
2000 |
|
| MDA |
19991108 |
|
| MMR |
20130709 |
|
| MN |
D06.347.360.827 D27.505.696.399.450.360.827 |
|
| notation |
D020845 |
|
| prefLabel |
Selective Estrogen Receptor Modulators |
|
| TERMUI |
T365817 T365818 T358354 T365816 T365815 T365814 |
|
| TH |
NLM (2000) |
|
| tui |
T125 T121 |
|
| subClassOf |