Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D020522 http://purl.bioontology.org/ontology/MESH/D020522
Preferred Name	Lymphoma, Mantle-Cell
Definitions	A form of non-Hodgkin lymphoma having a usually diffuse pattern with both small and medium lymphocytes and small cleaved cells. It accounts for about 5% of adult non-Hodgkin lymphomas in the United States and Europe. The majority of mantle-cell lymphomas are associated with a t(11;14) translocation resulting in overexpression of the CYCLIN D1 gene (GENES, BCL-1).
Synonyms	Lymphomas, Mantle-Zone Lymphoma, Mantle Cell Lymphoma, Lymphocytic, Diffuse, Poorly-Differentiated Mantle Zone Lymphoma Lymphoma, Centrocytic Small-Cell Lymphocytic Lymphoma, Diffuse, Poorly Differentiated Lymphoma, Lymphocytic, Intermediate Centrocytic Small-Cell Lymphoma Lymphoma, Small-Cell, Centrocytic Small-Cell Lymphomas, Centrocytic Mantle-Cell Lymphoma Mantle-Zone Lymphomas Mantle-Zone Lymphoma Diffuse Lymphocytic Lymphoma, Poorly-Differentiated Mantle Cell Lymphoma Small-Cell Lymphoma, Centrocytic Lymphomas, Mantle-Cell Lymphoma, Mantle-Zone Mantle-Cell Lymphomas Lymphoma, Lymphocytic, Diffuse, Intermediate Differentiated Lymphomas, Centrocytic Small-Cell Lymphoma, Centrocytic Small Cell Diffuse Lymphocytic Lymphoma, Poorly Differentiated Lymphocytic Lymphoma, Diffuse, Poorly-Differentiated Centrocytic Small-Cell Lymphomas See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	A form of non-Hodgkin lymphoma having a usually diffuse pattern with both small and medium lymphocytes and small cleaved cells. It accounts for about 5% of adult non-Hodgkin lymphomas in the United States and Europe. The majority of mantle-cell lymphomas are associated with a t(11;14) translocation resulting in overexpression of the CYCLIN D1 gene (GENES, BCL-1).
altLabel	Lymphomas, Mantle-Zone Lymphoma, Mantle Cell Lymphoma, Lymphocytic, Diffuse, Poorly-Differentiated Mantle Zone Lymphoma Lymphoma, Centrocytic Small-Cell Lymphocytic Lymphoma, Diffuse, Poorly Differentiated Lymphoma, Lymphocytic, Intermediate Centrocytic Small-Cell Lymphoma Lymphoma, Small-Cell, Centrocytic Small-Cell Lymphomas, Centrocytic Mantle-Cell Lymphoma Mantle-Zone Lymphomas Mantle-Zone Lymphoma Diffuse Lymphocytic Lymphoma, Poorly-Differentiated Mantle Cell Lymphoma Small-Cell Lymphoma, Centrocytic Lymphomas, Mantle-Cell Lymphoma, Mantle-Zone Mantle-Cell Lymphomas Lymphoma, Lymphocytic, Diffuse, Intermediate Differentiated Lymphomas, Centrocytic Small-Cell Lymphoma, Centrocytic Small Cell Diffuse Lymphocytic Lymphoma, Poorly Differentiated Lymphocytic Lymphoma, Diffuse, Poorly-Differentiated Centrocytic Small-Cell Lymphomas See more See less
prefLabel	Lymphoma, Mantle-Cell
Machine permutation	2000; for LYMPHOMA, LYMPHOCYTIC, DIFFUSE, INTERMEDIATE; LYMPHOCYTIC LYMPHOMA, DIFFUSE, POORLY-DIFFERENTIATED; LYMPHOMA, CENTROCYTIC SMALL-CELL; LYMPHOMA, LYMPHOCYTIC, DIFFUSE, POORLY-DIFFERENTIATED; & LYMPHOMA, SMALL-CELL, CENTROCYTIC see LYMPHOMA, SMALL CLEAVED-CELL, DIFFUSE 1991-1999
HN	2000; for LYMPHOMA, LYMPHOCYTIC, DIFFUSE, INTERMEDIATE; LYMPHOCYTIC LYMPHOMA, DIFFUSE, POORLY-DIFFERENTIATED; LYMPHOMA, CENTROCYTIC SMALL-CELL; LYMPHOMA, LYMPHOCYTIC, DIFFUSE, POORLY-DIFFERENTIATED; & LYMPHOMA, SMALL-CELL, CENTROCYTIC use LYMPHOMA, SMALL CLEAVED-CELL, DIFFUSE 1991-1999
type	http://www.w3.org/2002/07/owl#Class
tui	T047 T191
TERMUI	T362653 T049079 T049074 T358571 T049078 T372756 T049075 T362502 T362503 T049076 T049073 See more See less
TH	NLM (2000) NLM (1991)
MMR	20180629
notation	D020522
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D019940 http://purl.bioontology.org/ontology/MESH/D019938
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T047 http://purl.bioontology.org/ontology/STY/T191
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000401 See more See less
FX	D019938 D019940
DX	20000101
cui	C4721414 C0751958
DC	1
MN	C20.683.515.761.480.525 C04.557.386.480.525 C15.604.515.569.480.525
AQL	BL CF CH CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UL UR VE VI
MDA	19991012
subClassOf	http://purl.bioontology.org/ontology/MESH/D008228

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