Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D020180
http://purl.bioontology.org/ontology/MESH/D020180
Preferred Name

Heteroduplex Analysis

Definitions
A method of detecting gene mutation by mixing PCR-amplified mutant and wild-type DNA followed by denaturation and reannealing. The resultant products are resolved by gel electrophoresis, with single base substitutions detectable under optimal electrophoretic conditions and gel formulations. Large base pair mismatches may also be analyzed by using electron microscopy to visualize heteroduplex regions.
Synonyms
Heteroduplex Analyses
Analysis, Heteroduplex
Analyses, Heteroduplex
Type http://www.w3.org/2002/07/owl#Class
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