loading...| Preferred Name | Mitogen-Activated Protein Kinase 1 | |
| Synonyms |
p42(Mapk) Kinase MAP Kinase, p42 p42 MAPK p42(Mapk) p42(Mitogen-Activated Protein Kinase) MAPK1 Mitogen-Activated Protein Kinase p42 MAP Kinase MAPK2 Mitogen Activated Protein Kinase Extracellular Signal-Regulated Kinase 2 MAPK1 Mitogen Activated Protein Kinase MAPK2 Mitogen-Activated Protein Kinase MAP Kinase 2 Mitogen Activated Protein Kinase 2 Mitogen Activated Protein Kinase 1 Extracellular Signal Regulated Kinase 2 Mitogen-Activated Protein Kinase 2 |
|
| Definitions |
A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D019950 |
|
| altLabel |
p42(Mapk) Kinase MAP Kinase, p42 p42 MAPK p42(Mapk) p42(Mitogen-Activated Protein Kinase) MAPK1 Mitogen-Activated Protein Kinase p42 MAP Kinase MAPK2 Mitogen Activated Protein Kinase Extracellular Signal-Regulated Kinase 2 MAPK1 Mitogen Activated Protein Kinase MAPK2 Mitogen-Activated Protein Kinase MAP Kinase 2 Mitogen Activated Protein Kinase 2 Mitogen Activated Protein Kinase 1 Extracellular Signal Regulated Kinase 2 Mitogen-Activated Protein Kinase 2 |
|
| AN |
Don't confuse MAP Kinase 2 with MAP KINASE KINASES referred to as MAP2 Kinases |
|
| AQL |
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C0170168 |
|
| DC |
1 |
|
| definition |
A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms. |
|
| DX |
19980101 |
|
| HN |
2005(1992) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
EC 2.7.11.24 |
|
| Machine permutation |
2000; see P42 MAP KINASE 2000-2004, see P42(MAPK) KINASE 1998-1999; P42(MAPK) KINASE was indexed under CALMODULIN-DEPENDENT PROTEIN KINASES 1994-1997, PROTEIN-TYROSINE KINASE 1992-1997, PROTEIN-SERINE-THREONINE KINASES 1993-1995 & PROTEIN KINASES 1992; ERK2 BRAIN KINASE PK40 was indexed under PROTEIN-SERINE-THREONINE KINASES 1995-1999; ERK2 was indexed under CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1998-1999, CALMODULIN-DEPENDENT KINASES 1994-1997, PROTEIN-SERINE-THREONINE KINASES 1992-1993 & PROTEIN KINASES 1992; ERK2 MBP-KINASE was indexed under CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1998-1999 & CALMODULIN-DEPENDENT KINASES 1994-1997 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C535150 http://purl.bioontology.org/ontology/MESH/C085697 http://purl.bioontology.org/ontology/MESH/C448499 |
|
| MDA |
19970702 |
|
| MMR |
20210521 |
|
| MN |
D12.776.476.563.567.249.500 D08.811.913.696.620.682.700.567.249.500 |
|
| notation |
D019950 |
|
| prefLabel |
Mitogen-Activated Protein Kinase 1 |
|
| TERMUI |
T059473 T571696 T059472 T484423 T059471 T572658 T059474 T365004 T572657 T572019 T059476 |
|
| TH |
NLM (2000) NLM (2005) NLM (2003) NLM (1998) |
|
| tui |
T116 T126 |
|
| subClassOf |