Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D019772 http://purl.bioontology.org/ontology/MESH/D019772
Preferred Name	Topotecan
Definitions	An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.
Synonyms	Hycamtamine SK&F104864A SKF-104864-A SKF 104864 A NSC 609699 Hydrochloride, Nogitecan 9-Dimethylaminomethyl-10-hydroxycamptothecin Hycamtin Topotecan Hydrochloride NSC-609699 SKF104864A Nogitecan Hydrochloride SK&F 104864 A Topotecan Monohydrochloride, (S)-Isomer Hydrochloride, Topotecan NSC609699 SK&F-104864-A 9 Dimethylaminomethyl 10 hydroxycamptothecin See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.
altLabel	Hycamtamine SK&F104864A SKF-104864-A SKF 104864 A NSC 609699 Hydrochloride, Nogitecan 9-Dimethylaminomethyl-10-hydroxycamptothecin Hycamtin Topotecan Hydrochloride NSC-609699 SKF104864A Nogitecan Hydrochloride SK&F 104864 A Topotecan Monohydrochloride, (S)-Isomer Hydrochloride, Topotecan NSC609699 SK&F-104864-A 9 Dimethylaminomethyl 10 hydroxycamptothecin See more See less
prefLabel	Topotecan
Machine permutation	98; TOPOTECAN was indexed under CAMPTOTHECIN/analogs & derivatives 1991-97
HN	98; use TOPOTECAN (NM) 1991-97
Mapped from	http://purl.bioontology.org/ontology/MESH/C105151 http://purl.bioontology.org/ontology/MESH/C419191 http://purl.bioontology.org/ontology/MESH/C419192 http://purl.bioontology.org/ontology/MESH/C419190 http://purl.bioontology.org/ontology/MESH/C496393 http://purl.bioontology.org/ontology/MESH/C427583 http://purl.bioontology.org/ontology/MESH/C475944 http://purl.bioontology.org/ontology/MESH/C410030 http://purl.bioontology.org/ontology/MESH/C410031 http://purl.bioontology.org/ontology/MESH/C512566 http://purl.bioontology.org/ontology/MESH/C434884 See more See less
type	http://www.w3.org/2002/07/owl#Class
isa	http://purl.bioontology.org/ontology/MESH/D059004
PA	D059004
tui	T109 T121
TERMUI	T058776 T058771 T058774 T058775 T058770 T529636 T058772 T359278 T058773 T058769 See more See less
TH	USAN (1990) NLM (2004) NLM (1999) FDA SRS (2014) INN (19XX) NLM (1998) See more See less
MMR	20170117
notation	D019772
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T121 http://purl.bioontology.org/ontology/STY/T109
RR	119413-54-6 (Topotecan Hydrochloride) 123948-87-8 (Topotecan) 956S425ZCY
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	19980101
cui	C0886549 C0146224 C0700913 C0700915 C4082294 C0700912 See more See less
DC	1
MN	D03.132.151.850
LT	TRD
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
Inverse of RB	7M7YKX2N15 956S425ZCY 0
MDA	19990101
subClassOf	http://purl.bioontology.org/ontology/MESH/D002166

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