loading...| Preferred Name | Helix-Turn-Helix Motifs | |
| Synonyms |
Helix Turn Helix Motifs Motif, HTH HTH Motif Motif, Helix-Turn-Helix Motifs, Helix-Turn-Helix HTH Motifs Helix-Turn-Helix Motif Motifs, HTH Motifs, Helix Turn Helix |
|
| Definitions |
The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9) |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D019077 |
|
| altLabel |
Helix Turn Helix Motifs Motif, HTH HTH Motif Motif, Helix-Turn-Helix Motifs, Helix-Turn-Helix HTH Motifs Helix-Turn-Helix Motif Motifs, HTH Motifs, Helix Turn Helix |
|
| AN |
do not confuse with HELIX-LOOP-HELIX MOTIFS |
|
| AQL |
DE GE IM PH RE |
|
| cui |
C0282642 |
|
| DC |
1 |
|
| definition |
The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9) |
|
| DX |
19960101 |
|
| HN |
96; was see HELIX-LOOP-HELIX MOTIFS 1994-95 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Inverse of RO | ||
| Machine permutation |
96; was see HELIX-LOOP-HELIX MOTIFS 1994-95 |
|
| MDA |
19950526 |
|
| MMR |
20160531 |
|
| MN |
G02.111.570.820.709.275.500.360.360 |
|
| notation |
D019077 |
|
| OL |
use HELIX-LOOP-HELIX MOTIFS to search HELIX-TURN-HELIX MOTIFS 1994-95 |
|
| prefLabel |
Helix-Turn-Helix Motifs |
|
| TERMUI |
T362149 T056976 T362150 |
|
| TH |
NLM (1996) NLM (2000) |
|
| tui |
T082 |
|
| subClassOf |