Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D018902
http://purl.bioontology.org/ontology/MESH/D018902
Preferred Name

Chondrodysplasia Punctata, Rhizomelic

Definitions
An autosomal recessive form of CHONDRODYSPLASIA PUNCTATA characterized by defective plasmalogen biosynthesis and impaired peroxisomes. Patients have shortened proximal limbs and severely disturbed endochondral bone formation. The metabolic defects associated with the impaired peroxisomes are present only in the rhizomelic form of chondrodysplasia punctata. (From Scriver et al, Metabolic Basis of Inherited Disease, 6th ed, p1497)
Synonyms
Chondrodysplasia Punctatas, Rhizomelic
Chondrodysplasia Punctata, Rhizomelic Form
Punctata, Rhizomelic Chondrodysplasia
Rhizomelic Chondrodysplasia Punctata
Rhizomelic Chondrodysplasia Punctatas
Punctatas, Rhizomelic Chondrodysplasia
Type http://www.w3.org/2002/07/owl#Class
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