loading...| Preferred Name |
Genes, erbA |
|
| Synonyms |
v erbA Genes |
|
| Definitions |
Viral oncogenes that are homologues of erbA1 (THRA) gene which encodes thyroid hormone receptor alpha. v-erbA Oncogenes potentiate the transforming ability of other oncogenes such as v-erbB by inhibiting spontaneous differentiation of already transformed cells. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D018776 |
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| altLabel |
v erbA Genes Genes, erbA beta Genes, TR alpha Genes, erbA alpha alpha Gene, TR TR beta Genes THRA Gene TR beta Gene c erbA Proto Oncogenes Gene, THRA beta Genes, TR Genes, THRB erbA Gene erbA alpha Gene v erbA Oncogenes Gene, THRB v-erbA Genes erbA-beta Gene erbA-alpha Genes TR-alpha Gene c erbA Genes beta Gene, erbA TR-beta Gene alpha Genes, erbA THRB Gene TR alpha Gene alpha Gene, erbA THRB Genes Genes, erbA-beta TR alpha Genes beta Gene, TR beta Genes, erbA TR-beta Genes alpha Genes, TR erbA-alpha Gene erbA-beta Genes Genes, THRA TR-alpha Genes Genes, TR beta Genes, erbA-alpha erbA beta Genes v-erbA Oncogene v-erbA Oncogenes erbA alpha Genes erbA Genes erbA beta Gene THRA Genes c-erbA Proto-Oncogene v-erbA Gene c-erbA Genes c-erbA Gene Genes, TR-alpha Genes, TR-beta c-erbA Proto-Oncogenes |
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| AN |
erbA stands for "ERythroBlastosis virus, Avian"; GENES, ERBB & its specifics are also available; in titles & translations spell as erbA |
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| AQL |
DE ES GE IM PH RE |
|
| cui |
C0242988 C0242989 C0242991 C0242990 C0242987 |
|
| DC |
1 |
|
| definition |
Viral oncogenes that are homologues of erbA1 (THRA) gene which encodes thyroid hormone receptor alpha. v-erbA Oncogenes potentiate the transforming ability of other oncogenes such as v-erbB by inhibiting spontaneous differentiation of already transformed cells. Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity. |
|
| DX |
19950101 |
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| FX |
D018774 D011988 |
|
| HN |
95 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
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| Inverse of RO | ||
| Machine permutation |
95 |
|
| MDA |
19940523 |
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| MMR |
20080708 |
|
| MN |
G05.360.340.024.340.375.500.791.290 |
|
| notation |
D018776 |
|
| prefLabel |
Genes, erbA |
|
| TERMUI |
T055911 T055916 T479645 T055920 T055917 T055918 T055914 T055912 T055909 T055921 T055913 T055915 T055908 T479646 T055910 T055919 |
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| TH |
NLM (1995) NLM (2003) |
|
| tui |
T028 |
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| subClassOf |