loading...| Preferred Name |
Genes, erbB-2 |
|
| Synonyms |
HER2 Genes |
|
| Definitions |
The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D018734 |
|
| altLabel |
HER2 Genes erbb2 Genes erbB-2 Genes HER-2 Gene c erbB 2 Genes Gene, erbb2 neu Gene c erbB 2 Proto Oncogenes Gene, HER2 Genes, HER2 neu Genes c-erbB-2 Proto-Oncogenes erbb2 Gene Genes, neu Genes, erbb2 HER2 Gene Genes, HER-2 c-erbB-2 Gene c-erbB-2 Proto-Oncogene c-erbB-2 Genes erbB-2 Gene HER-2 Genes erbB 2 Genes |
|
| AN |
in titles & translations spell as erbB-2; GENES, ERBB-1 is also available |
|
| AQL |
DE ES GE IM PH RE |
|
| cui |
C0242957 |
|
| DC |
1 |
|
| definition |
The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2. |
|
| DX |
19950101 |
|
| FX |
D066246 D018719 D018739 |
|
| HN |
1995 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D018739 |
|
| Machine permutation |
1995 |
|
| MDA |
19940523 |
|
| MMR |
20180612 |
|
| MN |
G05.360.340.024.340.375.500.791.295.305 |
|
| notation |
D018734 |
|
| prefLabel |
Genes, erbB-2 |
|
| TERMUI |
T055799 T373111 T055794 T055798 T055797 T362166 T055795 T055796 |
|
| TH |
NLM (2000) NLM (1995) |
|
| tui |
T028 |
|
| subClassOf |