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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D018664
http://purl.bioontology.org/ontology/MESH/D018664
|
|---|---|
| Preferred Name | Interleukin-12 |
| Definitions |
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.
|
| Synonyms |
Interleukin-12 p70
IL 12
Cytotoxic Lymphocyte Maturation Factor
Natural Killer Cell Stimulatory Factor
IL12
IL-12
Edodekin Alfa
Interleukin 12 p70
IL-12 p70
Interleukin 12
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS. |
|---|---|
| altLabel |
Interleukin-12 p70
IL 12
Cytotoxic Lymphocyte Maturation Factor
Natural Killer Cell Stimulatory Factor
IL12
IL-12
Edodekin Alfa
Interleukin 12 p70
IL-12 p70
Interleukin 12
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|
| prefLabel | Interleukin-12
|
| Machine permutation | 1995; INTERLEUKIN 12 was indexed under INTERLEUKINS 1991-1994; INTERLEUKIN-12 P70 was indexed under INTERLEUKIN-12 2003-2006
|
| HN | 1995 (1991)
|
| Mapped from | |
| type | |
| isa | |
| PA |
D020533
D000276
|
| tui |
T116
T129
T121
|
| TERMUI |
T373474
T055565
T669076
T055566
T550497
T055561
T669102
T055563
T429787
T055562
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|
| TH |
USAN (1998)
NLM (2000)
NLM (1995)
NLM (2007)
|
| MMR | 20181010
|
| notation | D018664
|
| Inverse of RO | |
| Semantic type UMLS property | |
| Inverse of AQ |
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|
| FX |
D007111
D000069549
|
| DX | 19950101
|
| cui |
C3665495
C0123759
|
| DC | 1
|
| MN |
D12.644.276.374.465.512
D12.776.467.374.465.512
D23.529.374.465.512
|
| AQL | AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR
|
| Inverse of RB |
187348-17-0
0
|
| MDA | 19990101
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |