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Last uploaded: January 31, 2024

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Preferred Name	Gelsolin
Synonyms	Serum Actin Inhibitory Protein Gelsolin Protein
Definitions	A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.
ID	http://purl.bioontology.org/ontology/MESH/D018260
altLabel	Serum Actin Inhibitory Protein Gelsolin Protein
AQL	AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C0061187
DC	1
definition	A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.
DX	19940101
HN	1994(1980)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
Machine permutation	1994; GELSOLIN was indexed under CALCIUM-BINDING PROTEINS and MICROFILAMENT PROTEINS 1980-1993; SERUM ACTIN IHIBITORY PROTEIN was indexed under MICROFILAMENT PROTEINS 1988-2005, & under MUSCLE PROTEINS & PROTEINS 1986-1987
Mapped from	http://purl.bioontology.org/ontology/MESH/C016953 http://purl.bioontology.org/ontology/MESH/C098178 http://purl.bioontology.org/ontology/MESH/C527698 http://purl.bioontology.org/ontology/MESH/C065395 http://purl.bioontology.org/ontology/MESH/C525449 http://purl.bioontology.org/ontology/MESH/C558462 http://purl.bioontology.org/ontology/MESH/C117419 http://purl.bioontology.org/ontology/MESH/C098726
MDA	19930603
MMR	20170630
MN	D12.776.220.525.350 D12.776.476.387.437 D12.644.360.372.437 D05.750.078.730.350 D12.776.157.125.412.437
notation	D018260
prefLabel	Gelsolin
TERMUI	T121223 T054556 T638121
TH	NLM (1994) NLM (2006)
tui	T116 T123
subClassOf	http://purl.bioontology.org/ontology/MESH/D052139 http://purl.bioontology.org/ontology/MESH/D008840

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/CSP/2446-7400	CRISP	CUI
http://purl.bioontology.org/ontology/SNMI/F-62D50	SNMI	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/5086000	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SCTSPA/5086000	SCTSPA	CUI
http://purl.bioontology.org/ontology/MSHFRE/D018260	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000170617	NDFRT	CUI
http://www.orpha.net/ORDO/Orphanet_122296	ORDO	LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Gelsolin	SEPON	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.157.125.412.437	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0018493	OMIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C150253	BERO	LOOM
http://www.ncbi.nlm.nih.gov/gene/227753	NIFSTD	LOOM
http://purl.bioontology.org/ontology/CSP/2446-7400	CRISP	LOOM
http://id.nlm.nih.gov/mesh/D018260	MDM	LOOM
http://purl.bioontology.org/ontology/SNMI/F-62D50	SNMI	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.220.525.350	RH-MESH	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/5086000	SNOMEDCT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.476.387.437	RH-MESH	LOOM
http://purl.bioontology.org/ontology/OMIM/137350	OMIM	LOOM
http://purl.org/obo/owlapi/fma#FMA_67709	BIOMODELS	LOOM
http://scai.fraunhofer.de/MSOntology#Gelsolin	MSO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.360.381.437	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D018260	RH-MESH	LOOM
http://purl.obolibrary.org/obo/dinto_3761	DINTO	LOOM
http://www.orpha.net/ORDO/Orphanet_122296	ORDO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D05.750.078.730.350	RH-MESH	LOOM
http://purl.jp/bio/4/id/200906021347302477	IOBC	LOOM
http://purl.obolibrary.org/obo/PR_000002202	PR	LOOM
http://purl.obolibrary.org/obo/PR_000002202	NIFSTD	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150253	NCIT	LOOM
http://purl.obolibrary.org/obo/MESH_D018260	BERO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018871	PMAPP-PMO	LOOM
http://purl.org/sig/ont/fma/fma67709	FMA	LOOM