Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D018240
http://purl.bioontology.org/ontology/MESH/D018240
Preferred Name

Endodermal Sinus Tumor

Definitions
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)
Synonyms
Tumors, Yolk Sac
Tumor, Endodermal Sinus
Tumor, Yolk Sac
Yolk Sac Tumors
Tumors, Endodermal Sinus
Yolk Sac Tumor
Endodermal Sinus Tumors
Type http://www.w3.org/2002/07/owl#Class
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