loading...| Preferred Name |
Immunoglobulin Class Switching |
|
| Synonyms |
Switching, Ig Class |
|
| Definitions |
Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D017578 |
|
| altLabel |
Switching, Ig Class Isotype Switchings Class Switchings, Immunoglobulin Isotype Switching Class Switching Class Switching, Immunoglobulin Switching, Immunoglobulin Class Switching, Isotype Immunoglobulin Class Switchings Switchings, Isotype Class Switchings, Ig Ig Class Switchings Class Switchings Switchings, Class Switchings, Ig Class Ig Class Switching Switching, Class Class Switching, Ig Switchings, Immunoglobulin Class |
|
| AQL |
DE ES GE IM PH RE |
|
| cui |
C0206071 |
|
| DC |
1 |
|
| definition |
Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing. |
|
| DX |
19940101 |
|
| HN |
94 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Inverse of RO | ||
| Machine permutation |
94 |
|
| MDA |
19930617 |
|
| MMR |
20190705 |
|
| MN |
G12.500.274.501.450 G05.344.401.501.450 |
|
| notation |
D017578 |
|
| prefLabel |
Immunoglobulin Class Switching |
|
| TERMUI |
T000952297 T052708 T052707 T052706 |
|
| TH |
NLM (2020) NLM (1994) |
|
| tui |
T045 |
|
| subClassOf |