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Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D017578
http://purl.bioontology.org/ontology/MESH/D017578
|
|---|---|
| Preferred Name | Immunoglobulin Class Switching |
| Definitions |
Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.
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| Synonyms |
Switching, Ig Class
Isotype Switchings
Class Switchings, Immunoglobulin
Isotype Switching
Class Switching
Class Switching, Immunoglobulin
Switching, Immunoglobulin Class
Switching, Isotype
Immunoglobulin Class Switchings
Switchings, Isotype
Class Switchings, Ig
Ig Class Switchings
Class Switchings
Switchings, Class
Switchings, Ig Class
Ig Class Switching
Switching, Class
Class Switching, Ig
Switchings, Immunoglobulin Class
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing. |
|---|---|
| altLabel |
Switching, Ig Class
Isotype Switchings
Class Switchings, Immunoglobulin
Isotype Switching
Class Switching
Class Switching, Immunoglobulin
Switching, Immunoglobulin Class
Switching, Isotype
Immunoglobulin Class Switchings
Switchings, Isotype
Class Switchings, Ig
Ig Class Switchings
Class Switchings
Switchings, Class
Switchings, Ig Class
Ig Class Switching
Switching, Class
Class Switching, Ig
Switchings, Immunoglobulin Class
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|
| prefLabel |
Immunoglobulin Class Switching
|
| TH |
NLM (2020)
NLM (1994)
|
| notation |
D017578
|
| DX |
19940101
|
| Machine permutation |
94
|
| MN |
G12.500.274.501.450
G05.344.401.501.450
|
| MMR |
20190705
|
| AQL |
DE ES GE IM PH RE
|
| HN |
94
|
| subClassOf | |
| Semantic type UMLS property | |
| DC |
1
|
| MDA |
19930617
|
| Inverse of RO | |
| type | |
| tui |
T045
|
| cui |
C0206071
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| Inverse of AQ |
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|
| TERMUI |
T000952297
T052708
T052707
T052706
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