loading...| Preferred Name | Complement Factor I | |
| Synonyms |
C3b Inactivator Complement C4b C3b Inactivator Inactivator, C3b-C4b C4bC3bINA C3b-C4b Inactivator C4b C3b INA Complement 3b Complement 4b Inactivator C4b-C3b Inactivator, Complement C4b-C3b-INA Complement 3b-Complement 4b Inactivator Complement C4b-C3b Inactivator C3b C4b Inactivator Inactivator, C3b Inactivator, Complement C4b-C3b |
|
| Definitions |
A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D017244 |
|
| altLabel |
C3b Inactivator Complement C4b C3b Inactivator Inactivator, C3b-C4b C4bC3bINA C3b-C4b Inactivator C4b C3b INA Complement 3b Complement 4b Inactivator C4b-C3b Inactivator, Complement C4b-C3b-INA Complement 3b-Complement 4b Inactivator Complement C4b-C3b Inactivator C3b C4b Inactivator Inactivator, C3b Inactivator, Complement C4b-C3b |
|
| AN |
do not confuse with FACTOR I see FIBRINOGEN |
|
| AQL |
AD AE AG AI AN BI CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C0110533 |
|
| DC |
1 |
|
| definition |
A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator. |
|
| DX |
19930101 |
|
| HN |
93; was FACTOR I, C 3B INACTIVATOR (NM) 1983-92 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
EC 3.4.21.45 |
|
| isa | ||
| Machine permutation |
93; COMPLEMENT FACTOR I was indexed under SERINE PROTEINASES 1988-92 & under PEPTIDE PEPTIDOHYDROLASES 1983-87 |
|
| Mapped from | ||
| MDA |
19920507 |
|
| MMR |
20090706 |
|
| MN |
D08.811.277.656.959.350.210 D12.776.124.486.274.920.325.210 D08.811.277.656.300.760.210 |
|
| notation |
D017244 |
|
| OL |
use COMPLEMENT FACTOR I (NM) to search FACTOR I, C 3B INACTIVATOR 1983-92 |
|
| PA |
D051056 |
|
| prefLabel |
Complement Factor I |
|
| TERMUI |
T122015 T621749 T051406 T122017 T122012 T601207 T601208 |
|
| TH |
NLM (1993) NLM (2006) |
|
| tui |
T116 T129 T126 |
|
| subClassOf |