| Preferred Name |
Interferon-alpha
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| Synonyms |
Interferon alpha-J
Leukocyte Interferon
Lymphoblastoid Interferon
Interferon alpha 1
Interferon alpha-1
Interferon alpha J
Interferon alpha-T
IFN alpha D
LeIF I
alpha Interferon
Interferon Alfa
Leif D
Interferon alpha5
Lymphoblast Interferon
Interferon, Lymphoblast
Interferon alpha-4
IFN alpha5
Interferon alpha 17
Interferon, alpha
Interferon alpha 4
Interferon alpha 5
Interferon, Lymphoblastoid
Interferon, Leukocyte
LeIF J
Interferon alpha4
Interferon alpha-7
Interferon alpha-88
Interferon alpha 7
Interferon alpha T
alpha-Interferon
Interferon alpha 88
IFN-alpha5
Interferon alpha-17
Interferon alpha
IFN-alpha D
Interferon alpha-5
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| Definitions |
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
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| ID |
http://purl.bioontology.org/ontology/MESH/D016898
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| altLabel |
Interferon alpha-J Leukocyte Interferon Lymphoblastoid Interferon Interferon alpha 1 Interferon alpha-1 Interferon alpha J Interferon alpha-T IFN alpha D LeIF I alpha Interferon Interferon Alfa Leif D Interferon alpha5 Lymphoblast Interferon Interferon, Lymphoblast Interferon alpha-4 IFN alpha5 Interferon alpha 17 Interferon, alpha Interferon alpha 4 Interferon alpha 5 Interferon, Lymphoblastoid Interferon, Leukocyte LeIF J Interferon alpha4 Interferon alpha-7 Interferon alpha-88 Interferon alpha 7 Interferon alpha T alpha-Interferon Interferon alpha 88 IFN-alpha5 Interferon alpha-17 Interferon alpha IFN-alpha D Interferon alpha-5
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| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
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| cui |
C1098214 C3887953 C3887954 C0002199 C0391393 C0219697
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| DC |
1
|
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| definition |
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
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| DX |
19920101
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| HN |
1992; for INTERFERON, LYMPHOBLAST and INTERFERON, LEUKOCYTE use INTERFERON TYPE I 1989-1991
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| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
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| Inverse of RB |
0
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| isa |
http://purl.bioontology.org/ontology/MESH/D007155 http://purl.bioontology.org/ontology/MESH/D000998
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| Machine permutation |
1992; see INTERFERON TYPE I 1983-1991, INTERFERON ALPHA-1 was indexed under INTERFERON-ALPHA 2001-2011, INTERFERON-ALPHA 2 was indexed under INTERFERON-ALPHA 1997-2011, INTERFERON ALPHA4 was indexed under INTERFERON-ALPHA 1993-2001, INTERFERON ALPHA5 was indexed under INTERFERON-ALPHA 1996-2001
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| Mapped from |
http://purl.bioontology.org/ontology/MESH/C554162 http://purl.bioontology.org/ontology/MESH/C554163 http://purl.bioontology.org/ontology/MESH/C554160 http://purl.bioontology.org/ontology/MESH/C554164 http://purl.bioontology.org/ontology/MESH/C000621575 http://purl.bioontology.org/ontology/MESH/C000724048 http://purl.bioontology.org/ontology/MESH/C047910 http://purl.bioontology.org/ontology/MESH/C554783 http://purl.bioontology.org/ontology/MESH/C471357 http://purl.bioontology.org/ontology/MESH/C504514 http://purl.bioontology.org/ontology/MESH/C504513 http://purl.bioontology.org/ontology/MESH/C118689 http://purl.bioontology.org/ontology/MESH/C076799 http://purl.bioontology.org/ontology/MESH/C090879 http://purl.bioontology.org/ontology/MESH/C531108 http://purl.bioontology.org/ontology/MESH/C554129 http://purl.bioontology.org/ontology/MESH/C554126 http://purl.bioontology.org/ontology/MESH/C000711828 http://purl.bioontology.org/ontology/MESH/C412623 http://purl.bioontology.org/ontology/MESH/C050739 http://purl.bioontology.org/ontology/MESH/C452189 http://purl.bioontology.org/ontology/MESH/C080665 http://purl.bioontology.org/ontology/MESH/C554150 http://purl.bioontology.org/ontology/MESH/C554156 http://purl.bioontology.org/ontology/MESH/C554158 http://purl.bioontology.org/ontology/MESH/C554159 http://purl.bioontology.org/ontology/MESH/C120240 http://purl.bioontology.org/ontology/MESH/C100416 http://purl.bioontology.org/ontology/MESH/C068567 http://purl.bioontology.org/ontology/MESH/C114167 http://purl.bioontology.org/ontology/MESH/C085827 http://purl.bioontology.org/ontology/MESH/C473631 http://purl.bioontology.org/ontology/MESH/C120238 http://purl.bioontology.org/ontology/MESH/C120239 http://purl.bioontology.org/ontology/MESH/C554329 http://purl.bioontology.org/ontology/MESH/C554326 http://purl.bioontology.org/ontology/MESH/C554324 http://purl.bioontology.org/ontology/MESH/C554325 http://purl.bioontology.org/ontology/MESH/C554327 http://purl.bioontology.org/ontology/MESH/C438724 http://purl.bioontology.org/ontology/MESH/C417083 http://purl.bioontology.org/ontology/MESH/C058673 http://purl.bioontology.org/ontology/MESH/C554330 http://purl.bioontology.org/ontology/MESH/C554334 http://purl.bioontology.org/ontology/MESH/C554331 http://purl.bioontology.org/ontology/MESH/C554333 http://purl.bioontology.org/ontology/MESH/C554332 http://purl.bioontology.org/ontology/MESH/C472347 http://purl.bioontology.org/ontology/MESH/C472348 http://purl.bioontology.org/ontology/MESH/C044342 http://purl.bioontology.org/ontology/MESH/C501864 http://purl.bioontology.org/ontology/MESH/C571406 http://purl.bioontology.org/ontology/MESH/C577353 http://purl.bioontology.org/ontology/MESH/C543152 http://purl.bioontology.org/ontology/MESH/C521991 http://purl.bioontology.org/ontology/MESH/C056556 http://purl.bioontology.org/ontology/MESH/C111627 http://purl.bioontology.org/ontology/MESH/C040774 http://purl.bioontology.org/ontology/MESH/C040773 http://purl.bioontology.org/ontology/MESH/C113934 http://purl.bioontology.org/ontology/MESH/C519328 http://purl.bioontology.org/ontology/MESH/C469326
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| MDA |
19910530
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| MMR |
20180111
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| MN |
D23.529.374.440.890.250 D12.644.276.374.440.890.250 D12.776.467.374.440.890.250
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| notation |
D016898
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| PA |
D000998 D007155
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| prefLabel |
Interferon-alpha
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| TERMUI |
T782163 T782161 T050583 T050581 T050582 T782160 T782166 T782202 T782165 T050584 T050587 T782164 T784696 T294083 T467477 T782201 T782199 T050585 T050590 T782200 T782198 T782162
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| TH |
NLM (2012) NLM (1992)
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| tui |
T116 T129 T121
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| subClassOf |
http://purl.bioontology.org/ontology/MESH/D007370
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