loading...| Preferred Name |
Bone Remodeling |
|
| Synonyms |
Turnover, Bone Bone Turnover Bone Turnovers Turnovers, Bone Remodeling, Bone |
|
| Definitions |
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D016723 |
|
| altLabel |
Turnover, Bone Bone Turnover Bone Turnovers Turnovers, Bone Remodeling, Bone |
|
| AN |
note category: an aspect of bone physiol |
|
| AQL |
DE GE IM PH RE |
|
| cui |
C0085268 |
|
| DC |
1 |
|
| definition |
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS. |
|
| DX |
19920101 |
|
| HN |
92 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Machine permutation |
92 |
|
| MDA |
19910429 |
|
| MMR |
20160602 |
|
| MN |
G11.427.213 G16.762.150 |
|
| notation |
D016723 |
|
| prefLabel |
Bone Remodeling |
|
| TERMUI |
T050113 T000874154 |
|
| TH |
NLM (2016) NLM (1992) |
|
| tui |
T042 |
|
| subClassOf |