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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D016704
http://purl.bioontology.org/ontology/MESH/D016704
|
|---|---|
| Preferred Name | Synapsins |
| Definitions |
A family of synaptic vesicle-associated proteins involved in the short-term regulation of NEUROTRANSMITTER release. Synapsin I, the predominant member of this family, links SYNAPTIC VESICLES to ACTIN FILAMENTS in the presynaptic nerve terminal. These interactions are modulated by the reversible PHOSPHORYLATION of synapsin I through various signal transduction pathways. The protein is also a substrate for cAMP- and CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES. It is believed that these functional properties are also shared by synapsin II.
|
| Synonyms |
Synapsin II
Synapsin
Synapsin I
Synapsin III
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A family of synaptic vesicle-associated proteins involved in the short-term regulation of NEUROTRANSMITTER release. Synapsin I, the predominant member of this family, links SYNAPTIC VESICLES to ACTIN FILAMENTS in the presynaptic nerve terminal. These interactions are modulated by the reversible PHOSPHORYLATION of synapsin I through various signal transduction pathways. The protein is also a substrate for cAMP- and CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES. It is believed that these functional properties are also shared by synapsin II. |
|---|---|
| altLabel |
Synapsin II
Synapsin
Synapsin I
Synapsin III
|
| prefLabel | Synapsins
|
| Machine permutation | 1992
|
| HN | 1992; use SYNAPSINS (NM) 1981-1991
|
| Mapped from | |
| type | |
| tui |
T116
T123
|
| TERMUI |
T050055
T553884
T000996726
T050058
T050059
|
| TH |
NLM (2005)
NLM (1992)
NLM (2021)
|
| MMR | 20200527
|
| notation | D016704
|
| Semantic type UMLS property | |
| Inverse of AQ |
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|
| DX | 19920101
|
| cui |
C0087045
C1456397
C0085252
C0087044
|
| DC | 1
|
| MN |
D12.776.631.750
D12.776.744.840
|
| AQL | AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
| Inverse of RB | 0
|
| MDA | 19990101
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |