Medical Subject Headings

Last uploaded: August 28, 2024
Preferred Name

Leucine Zippers
Synonyms

Zipper, Leucine

Zippers, Leucine

Leucine Zipper

Definitions

DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped structures. Leucines occurring in heptad repeats end up on the same sides of the helixes and are adjacent to each other in the stem of the Y (the "zipper" region). The DNA-binding residues are located in the bifurcated region of the Y.

ID

http://purl.bioontology.org/ontology/MESH/D016350

altLabel

Zipper, Leucine

Zippers, Leucine

Leucine Zipper

AQL

DE GE IM PH RE

cui

C0079686

DC

1

definition

DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped structures. Leucines occurring in heptad repeats end up on the same sides of the helixes and are adjacent to each other in the stem of the Y (the "zipper" region). The DNA-binding residues are located in the bifurcated region of the Y.

DX

19910101

HN

91

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000187

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000528

Inverse of RO

http://purl.bioontology.org/ontology/MESH/D004268

http://purl.bioontology.org/ontology/MESH/D051778

Machine permutation

91

MDA

19900529

MMR

20160531

MN

G02.111.570.820.709.275.500.520

notation

D016350

prefLabel

Leucine Zippers

TERMUI

T048835

TH

NLM (1991)

tui

T116

subClassOf

http://purl.bioontology.org/ontology/MESH/D020816

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