loading...| Preferred Name | Zinc Fingers | |
| Synonyms |
Finger, Zinc Zinc Finger DNA-Binding Domains Motif, Zinc Finger Motifs, Zinc Finger Zinc Finger DNA Binding Domains Fingers, Zinc Zinc Finger Motif Zinc Finger Motifs Zinc Finger |
|
| Definitions |
Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D016335 |
|
| altLabel |
Finger, Zinc Zinc Finger DNA-Binding Domains Motif, Zinc Finger Motifs, Zinc Finger Zinc Finger DNA Binding Domains Fingers, Zinc Zinc Finger Motif Zinc Finger Motifs Zinc Finger |
|
| AQL |
DE GE IM PH RE |
|
| cui |
C0080347 C4505463 |
|
| DC |
1 |
|
| definition |
Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites. |
|
| DX |
19910101 |
|
| HN |
91 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D004268 http://purl.bioontology.org/ontology/MESH/D050882 http://purl.bioontology.org/ontology/MESH/D034802 |
|
| Machine permutation |
91 |
|
| Mapped from | ||
| MDA |
19900529 |
|
| MMR |
20170630 |
|
| MN |
G02.111.570.820.709.275.500.985 |
|
| notation |
D016335 |
|
| prefLabel |
Zinc Fingers |
|
| TERMUI |
T048749 T000924134 T362158 |
|
| TH |
NLM (2000) NLM (1991) NLM (2018) |
|
| tui |
T087 |
|
| subClassOf |