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Medical Subject Headings
| Id | http://purl.bioontology.org/ontology/MESH/D016222
http://purl.bioontology.org/ontology/MESH/D016222
|
|---|---|
| Preferred Name | Fibroblast Growth Factor 2 |
| Definitions |
A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).
|
| Synonyms |
FGF-2
HBGF-2
Basic Fibroblast Growth Factor
Cartilage Derived Growth Factor
FGF 2
Prostate Epithelial Cell Growth Factor
Prostatropin
Class II Heparin-Binding Growth Factor
Fibroblast Growth Factor-2
Heparin-Binding Growth Factor Class II
Cartilage-Derived Growth Factor
FGF2
Fibroblast Growth Factor, Basic
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1). |
|---|---|
| altLabel |
FGF-2
HBGF-2
Basic Fibroblast Growth Factor
Cartilage Derived Growth Factor
FGF 2
Prostate Epithelial Cell Growth Factor
Prostatropin
Class II Heparin-Binding Growth Factor
Fibroblast Growth Factor-2
Heparin-Binding Growth Factor Class II
Cartilage-Derived Growth Factor
FGF2
Fibroblast Growth Factor, Basic
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|
| prefLabel |
Fibroblast Growth Factor 2
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| TH |
NLM (2002)
NLM (1991)
NLM (2007)
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| notation |
D016222
|
| DX |
19910101
|
| Machine permutation |
2001; FIBROBLAST GROWTH FACTOR-2 was indexed under FIBROBLAST GROWTH FACTOR, BASIC 1996-2001 & under FIBROBLAST GROWTH FACTOR 1995; PROSTATROPIN was indexed under NERVE TISSUE PROTEINS 1986-2001; CARTILAGE-DERIVED GROWTH FACTOR was indexed under PROTEINS 2005-2006
|
| MN |
D12.644.276.624.120
D23.529.624.120
D12.776.467.624.120
|
| MMR |
20130709
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| Mapped from | |
| AQL |
AA AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
| HN |
2001(1991); for FIBROBLAST GROWTH FACTOR-2 use FIBROBLAST GROWTH FACTOR 2 (NM) 1995; for PROSTATROPIN use FIBROBLAST GROWTH FACTOR 2 (NM) 1986-2001
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| subClassOf | |
| Semantic type UMLS property | |
| Inverse of RB |
103107-01-3
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| DC |
1
|
| MDA |
19900628
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| type | |
| tui |
T116
T123
|
| cui |
C0380603
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| Inverse of AQ |
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| TERMUI |
T280762
T280760
T048293
T048295
T170248
T642057
T170249
T048292
T048294
T048296
T280763
T280761
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