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Medical Subject Headings
| Preferred Name | Fibroblast Growth Factor 1 | |
| Synonyms |
Class I Heparin-Binding Growth Factor Heparin-Binding Growth Factor, Class I HBGF-1 FGF-1 Fibroblast growth factor (human brain acidic protein moiety reduced) Fibroblast Growth Factor-1 Heparin Binding Growth Factor, Class I Acidic Fibroblast Growth Factor Fibroblast Growth Factor, Acidic FGF1 Heparin-Binding Fibroblast Growth Factor Class I |
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| Definitions |
A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2). |
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| ID |
http://purl.bioontology.org/ontology/MESH/D016220 |
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| altLabel |
Class I Heparin-Binding Growth Factor Heparin-Binding Growth Factor, Class I HBGF-1 FGF-1 Fibroblast growth factor (human brain acidic protein moiety reduced) Fibroblast Growth Factor-1 Heparin Binding Growth Factor, Class I Acidic Fibroblast Growth Factor Fibroblast Growth Factor, Acidic FGF1 Heparin-Binding Fibroblast Growth Factor Class I
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| AQL |
AA AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
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| cui |
C0079349
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|
| DC |
1
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|
| definition |
A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).
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|
| DX |
19910101
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| HN |
2002(1991); for FIBROBLAST GROWTH FACTOR-1 use FIBROBLAST GROWTH FACTOR 1(NM) 1998-2001
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| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
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| Inverse of RB |
104781-85-3
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| Machine permutation |
2002; FIBROBLAST GROWTH FACTOR-1 was indexed under FIBROBLAST GROWTH FACTOR ACIDIC 2001, FIBROBLAST GROWTH FACTOR 2000-2001 & under FIBROBLAST GROWTH FACTOR, BASIC 1998-2000
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| Mapped from |
http://purl.bioontology.org/ontology/MESH/C557087 http://purl.bioontology.org/ontology/MESH/C103063 http://purl.bioontology.org/ontology/MESH/C554637 http://purl.bioontology.org/ontology/MESH/C480524 http://purl.bioontology.org/ontology/MESH/C121515 |
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| MDA |
19900705
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| MMR |
20060705
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|
| MN |
D12.644.276.624.110 D23.529.624.110 D12.776.467.624.110
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|
| notation |
D016220
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|
| prefLabel |
Fibroblast Growth Factor 1
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| TERMUI |
T048282 T048281 T048285 T326075 T326074 T440828 T326073 T048286 T048283 T048284
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| TH |
NLM (2002) NLM (1991)
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| tui |
T116 T123
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |