loading...| Preferred Name |
Maturation-Promoting Factor |
|
| Synonyms |
Histone H1 Kinase, Growth Associated Histone H1 Kinase, Growth-Associated Mitosis-Promoting Factor Histone H1 Kinase, M-Phase-Specific M Phase-Promoting Factor Maturation Promoting Factor Mitosis Promoting Factor M Phase Promoting Factor Histone H1 Kinase, M Phase Specific |
|
| Definitions |
Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D016200 |
|
| altLabel |
Histone H1 Kinase, Growth Associated Histone H1 Kinase, Growth-Associated Mitosis-Promoting Factor Histone H1 Kinase, M-Phase-Specific M Phase-Promoting Factor Maturation Promoting Factor Mitosis Promoting Factor M Phase Promoting Factor Histone H1 Kinase, M Phase Specific |
|
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR |
|
| cui |
C0079805 |
|
| DC |
1 |
|
| definition |
Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2. |
|
| DX |
19910101 |
|
| FX |
D016213 |
|
| HN |
91; HISTONE H1 KINASE, M-PHASE-SPECIFIC was HISTONE H1 KINASE, M PHASE-SPECIFIC 1991-93 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
EC 2.7.11.22 |
|
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D008540 |
|
| Machine permutation |
91; HISTONE H1 KINASE, M-PHASE-SPECIFIC was HISTONE H1 KINASE, M PHASE-SPECIFIC 1991-93 |
|
| Mapped from | ||
| MDA |
19900617 |
|
| MMR |
20210521 |
|
| MN |
D12.776.476.563.646.500.984 D08.811.913.696.620.682.700.646.500.984 D12.776.167.200.580 |
|
| notation |
D016200 |
|
| prefLabel |
Maturation-Promoting Factor |
|
| TERMUI |
T048171 T048169 T048172 T048173 T048170 |
|
| TH |
NLM (1991) |
|
| tui |
T116 T126 |
|
| subClassOf |