Preferred Name | Receptors, N-Methyl-D-Aspartate | |
Synonyms |
NMDA Receptor Ionophore Complex Receptor, NMDA NMDA Receptor NMDA Receptors N Methyl D Aspartate Receptors N Methylaspartate Receptors Receptors, NMDA N-Methyl-D-Aspartate Receptor Receptors, N Methylaspartate Receptors, N Methyl D Aspartate Receptors, N-Methylaspartate N-Methylaspartate Receptors N-Methyl-D-Aspartate Receptors Receptor, N-Methyl-D-Aspartate N Methyl D Aspartate Receptor NMDA Receptor-Ionophore Complex |
|
Definitions |
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity. |
|
ID |
http://purl.bioontology.org/ontology/MESH/D016194 |
|
altLabel |
NMDA Receptor Ionophore Complex Receptor, NMDA NMDA Receptor NMDA Receptors N Methyl D Aspartate Receptors N Methylaspartate Receptors Receptors, NMDA N-Methyl-D-Aspartate Receptor Receptors, N Methylaspartate Receptors, N Methyl D Aspartate Receptors, N-Methylaspartate N-Methylaspartate Receptors N-Methyl-D-Aspartate Receptors Receptor, N-Methyl-D-Aspartate N Methyl D Aspartate Receptor NMDA Receptor-Ionophore Complex |
|
AQL |
AD AG AI AN BI BL CH CL DE DF GE HI IM IP ME PH RE TU UL |
|
cui |
C0080093 |
|
DC |
1 |
|
definition |
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity. |
|
DX |
19910101 |
|
HN |
93; was RECEPTOR, N-METHYL-D-ASPARTATE 1991-92; N-METHYL-D-ASPARTATE RECEPTORS was N-METHYL-D-ASPARTATE RECEPTOR see RECEPTOR, N-METHYL-D-ASPARTATE 1991-92 |
|
Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
Inverse of RB |
0 |
|
Inverse of RO | ||
Machine permutation |
93; was RECEPTOR, N-METHYL-D-ASPARTATE 1991-92; N-METHYL-D-ASPARTATE RECEPTORS was N-METHYL-D-ASPARTATE RECEPTOR see RECEPTOR, N-METHYL-D-ASPARTATE 1991-92 |
|
Mapped from |
http://purl.bioontology.org/ontology/MESH/C432823 http://purl.bioontology.org/ontology/MESH/C000619303 http://purl.bioontology.org/ontology/MESH/C409466 http://purl.bioontology.org/ontology/MESH/C121673 http://purl.bioontology.org/ontology/MESH/C486748 http://purl.bioontology.org/ontology/MESH/C549071 http://purl.bioontology.org/ontology/MESH/C485096 http://purl.bioontology.org/ontology/MESH/C436186 http://purl.bioontology.org/ontology/MESH/C548929 http://purl.bioontology.org/ontology/MESH/C574005 http://purl.bioontology.org/ontology/MESH/C580825 http://purl.bioontology.org/ontology/MESH/C120997 http://purl.bioontology.org/ontology/MESH/C464437 http://purl.bioontology.org/ontology/MESH/C464436 http://purl.bioontology.org/ontology/MESH/C440500 http://purl.bioontology.org/ontology/MESH/C000631568 http://purl.bioontology.org/ontology/MESH/C584082 http://purl.bioontology.org/ontology/MESH/C000629432 http://purl.bioontology.org/ontology/MESH/C485668 http://purl.bioontology.org/ontology/MESH/C533282 http://purl.bioontology.org/ontology/MESH/C473649 http://purl.bioontology.org/ontology/MESH/C501155 http://purl.bioontology.org/ontology/MESH/C531979 http://purl.bioontology.org/ontology/MESH/C121001 |
|
MDA |
19900531 |
|
MMR |
20200527 |
|
MN |
D12.776.543.585.400.500.200.500 D12.776.543.750.720.200.450.400.500 D12.776.157.530.400.400.500.500 D12.776.543.550.450.500.200.500 |
|
notation |
D016194 |
|
OL |
use RECEPTORS, N-METHYL-D-ASPARTATE to search RECEPTOR, N-METHYL-D-ASPARTATE & N-METHYL-D-ASPARTATE RECEPTOR 1991-92 |
|
prefLabel |
Receptors, N-Methyl-D-Aspartate |
|
TERMUI |
T048137 T048136 T048133 T048135 T048132 T000996330 T048134 T048138 T000996199 |
|
TH |
NLM (1993) NLM (1991) NLM (1994) NLM (2021) |
|
tui |
T116 T192 |
|
subClassOf |