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Medical Subject Headings
| Preferred Name | Complement Membrane Attack Complex | |
| Synonyms |
C5b-9 Complement Complex, Terminal C5b-8-poly-C9 C5b 8 poly C9 Cytolytic Terminal Complement Complex C 5b-9 Membrane Attack Complex Complement Complex C5b-9 Terminal Complement Complex Complex, Terminal Complement Complement Complex C5b 9 |
|
| Definitions |
A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the "membrane attack complex" or MAC. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D015938 |
|
| altLabel |
C5b-9 Complement Complex, Terminal C5b-8-poly-C9 C5b 8 poly C9 Cytolytic Terminal Complement Complex C 5b-9 Membrane Attack Complex Complement Complex C5b-9 Terminal Complement Complex Complex, Terminal Complement Complement Complex C5b 9
|
|
| AQL |
AD AE AG AI AN BI CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
|
| cui |
C0009545
|
|
| DC |
1
|
|
| definition |
A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the "membrane attack complex" or MAC.
|
|
| DX |
19900101
|
|
| HN |
90
|
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
0
|
|
| Inverse of RO | ||
| isa | ||
| Machine permutation |
90
|
|
| Mapped from | ||
| MDA |
19890525
|
|
| MMR |
20050630
|
|
| MN |
D12.776.124.486.274.930
|
|
| notation |
D015938
|
|
| PA |
D007155
|
|
| prefLabel |
Complement Membrane Attack Complex
|
|
| TERMUI |
T047300 T047296 T047297 T047302 T047301 T620384 T047299 T047298
|
|
| TH |
NLM (1991) NLM (1990) NLM (1992) NLM (2006)
|
|
| tui |
T116 T129
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
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