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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D015938
http://purl.bioontology.org/ontology/MESH/D015938
|
|---|---|
| Preferred Name | Complement Membrane Attack Complex |
| Definitions |
A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the membrane attack complex or MAC.
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| Synonyms |
C5b-9
Complement Complex, Terminal
C5b-8-poly-C9
C5b 8 poly C9
Cytolytic Terminal Complement Complex
C 5b-9
Membrane Attack Complex
Complement Complex C5b-9
Terminal Complement Complex
Complex, Terminal Complement
Complement Complex C5b 9
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the membrane attack complex or MAC. |
|---|---|
| altLabel |
C5b-9
Complement Complex, Terminal
C5b-8-poly-C9
C5b 8 poly C9
Cytolytic Terminal Complement Complex
C 5b-9
Membrane Attack Complex
Complement Complex C5b-9
Terminal Complement Complex
Complex, Terminal Complement
Complement Complex C5b 9
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| prefLabel | Complement Membrane Attack Complex
|
| Machine permutation | 90
|
| HN | 90
|
| Mapped from | |
| type | |
| isa | |
| PA | D007155
|
| tui |
T116
T129
|
| TERMUI |
T047300
T047296
T047297
T047302
T047301
T620384
T047299
T047298
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| TH |
NLM (1991)
NLM (1990)
NLM (1992)
NLM (2006)
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| MMR | 20050630
|
| notation | D015938
|
| Inverse of RO | |
| Semantic type UMLS property | |
| Inverse of AQ |
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| DX | 19900101
|
| cui | C0009545
|
| DC | 1
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| MN | D12.776.124.486.274.930
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| AQL | AD AE AG AI AN BI CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
| Inverse of RB | 0
|
| MDA | 19990101
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |